NCT04668898Completed
LRRK2, GBA and Other Genetic Biomarkers in Eastern European (Ashkenazi) Jews With and Without Parkinson's Disease
Dissecting Oligogenic Biomarkers in Ashkenazi Jews With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 16 Apr 2025
Brief summary (registry, in English)
Single site observational study focused on elucidating the genes and biochemical pathways involved in causing Parkinson disease.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 203 (actual)
- First submitted
- 9 Dec 2020
- Start date
- 1 Apr 2019
- Primary completion date
- 1 Apr 2025
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Diseases
- Parkinson disease
- NCT number
- NCT04668898
What you commit to
- Study type: Observational
- Participants enrolled: 203
- From 1 Apr 2019 to the primary completion date, 1 Apr 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- -Patients who do not have Parkinson disease or family members of Ashkenazi (Eastern European) Jewish descent who either has a GBA or LRRK2 mutations OR who has 3 or more family members with PD.
Who the study is looking for
- Parkinson disease patients and their family members and is limited to participants of Ashkenazi (Eastern European) Jewish descent with GBA and LRRK2 mutations, or with 3 or more family members with PD
- Participants must be local to the New York City area and willing to come to Mount Sinai Downtown for annual 2 hour study visits which include obtaining personal medical and family history information, blood, urine and spinal fluid samples, neurological exam and neuropsychiatric testing. Spinal fluid collection is encouraged but optional.
Age in the registry: 30 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mount Sinai-- Downtown Union Square Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.