NCT04670393Completed
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
Impact of the Administration of an Antioxidant Food Supplement Associated With Oral Probiotics on the Ovarian Oxidative Stress Profile and the Intestinal Microbiota Function in the in Vitro Fertilization Cycle of Patients With Polycystic Ovarian Syndrome
Source: ClinicalTrials.gov · Last updated 4 Dec 2025
Brief summary (registry, in English)
The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with polycystic ovarian syndrome
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 4 Dec 2020
- Start date
- 2 Dec 2020
- Primary completion date
- 23 Jan 2025
- Lead sponsor
- Fertypharm
- NCT number
- NCT04670393
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 2 Dec 2020 to the primary completion date, 23 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Hormonal contraceptive, insulin sensitizers such as metformin, inositols, antioxidants, vitamin supplements except folic acid, GnRH analogs, steroidal drugs or others with anti-inflammatory properties, antibiotics, probiotics, laxatives use in the 3 months prior to recruitment
- Endometriosis, hydrosalpinx not surgically treated, acute or chronic inflammatory diseases, systemic immune diseases, other endocrine diseases or dysfunctions except for PCOS and subclinical hypothyroidism treated with low doses of levothyroxine (eg congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, Diabetes Millitus, hyperprolactinemia, hyperglycemia), active neoplastic disease or without evidence of complete remission for at least 5 years,
Other illness
- Hypersensitivity to any of the components in the Fertybiotic Mujer Plus® formulation
Other
- Tobacco consumption in last 12 months
- Active participation in an active weight reduction program or hypocaloric diet during the study period. No change in habits will be taught during the study period
Who the study is looking for
- Age:18-38 years old
- Diagnosis of PCOS according to compliance with the Rotterdam criteria
- BMI \>= 25
Age in the registry: 18 years to 38 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Clinic Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.