NCT04677998Recruiting
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
Source: ClinicalTrials.gov · Last updated 23 Feb 2026
Brief summary (registry, in English)
The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1000 (estimated)
- First submitted
- 24 Nov 2020
- Start date
- 24 Nov 2020
- Primary completion date
- Nov 2026
- Lead sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- NCT number
- NCT04677998
What you commit to
- Study type: Observational
- Planned participants: 1000
- From 24 Nov 2020 to the primary completion date, Nov 2026
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Need for surgery
Other illness
- Gastric or duodenal cancer at baseline endoscopy
Other
- Endoscopic removal of all polyps with an indication for removal not possible/feasible
Who the study is looking for
- Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and/or clinical diagnosis (\>100 colorectal adenomas in combination with a positive family history of FAP)
- Age 18 years or older
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Academic Medical Centre Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Recruiting |
| MD Anderson Coordinator of this site? Confirm its status | Houston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.