NCT04678583Recruiting
Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer
Source: ClinicalTrials.gov · Last updated 13 Jun 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
the ARMANI trial will test the hypothesis, if an anatomic resection (AR) improves long-term outcome vs. a non-anatomical resection (NAR) in patients undergoing surgery for RAS-mutated colorectal liver metastasis (CRLM).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 240 (estimated)
- First submitted
- 30 Oct 2020
- Start date
- Jan 2021
- Primary completion date
- Dec 2027
- Lead sponsor
- Technische Universität Dresden
- Diseases
- Colorectal cancer
- NCT number
- NCT04678583
What you commit to
- Study type: Interventional
- Planned participants: 240
- From Jan 2021 to the primary completion date, Dec 2027
- 37 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Planned staged liver resection (e.g. two-stage hepatectomy)
- Diagnosis of another cancer \< 5 years prior to randomization Exceptions: curatively treated in situ cervical cancer, curatively resected non-melanoma skin cancer
Other illness
- Addiction or other illnesses which do not allow the person concerned to assess the nature and extent of the clinical trial and its possible consequences
Other
- Extrahepatic metastases
- Expected lack of compliance
Who the study is looking for
- Colorectal cancer with RAS mutation (KRAS or NRAS)
- Colorectal liver metastases (single or multiple)
- Planned R0 resection of liver metastases (and primary tumor, if present)
- Anatomical and non-anatomical liver resection technically feasible
- Male and female patients, age ≥ 18 years
- Written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (37)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Intestinal Center West Middle Franconia, ANregiomed Clinic Ansbach Coordinator of this site? Confirm its status | Ansbach | Germany | Recruiting |
| Clinic for General, Vizeral and Transplant Surgery, Augsburg University Hospital Coordinator of this site? Confirm its status | Augsburg | Germany | Recruiting |
| Department of General, Visceral and Vascular Surgery, Charité, University Medicine Berlin, Campus Benjamin Franklin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Recruiting |
| Clinic and Polyclinic for General, Visceral, Thoracic and Vascular Surgery, University Hospital Bonn Coordinator of this site? Confirm its status | Bonn | Germany | Recruiting |
| Surgical Clinic, Municipal Hospital Braunschweig gGmbH Coordinator of this site? Confirm its status | Braunschweig | Germany | Recruiting |
| Cancer Center, Helios Amper-Hospital Dachau Coordinator of this site? Confirm its status | Dachau | Germany | Recruiting |
| Surgical Clinic, Dortmund Hospital Coordinator of this site? Confirm its status | Dortmund | Germany | Recruiting |
| Clinic for General and Visceral Surgery, Municipal Hospital Dresden Coordinator of this site? Confirm its status | Dresden | Germany | Recruiting |
| Department of Gastrointestinal-, Thoracic and Vascular Surgery University Hospital Carl Gustav Carus Technische Universität Dresden Coordinator of this site? Confirm its status | Dresden | Germany | Recruiting |
| Clinic for General, Visceral and Pediatric Surgery, University Hospital Düsseldorf Coordinator of this site? Confirm its status | Düsseldorf | Germany | Recruiting |
| Surgical Clinic, University Hospital Erlangen Coordinator of this site? Confirm its status | Erlangen | Germany | Recruiting |
| Clinic for General, Visceral and Transplant Surgery, University Hospital Frankfurt, Goethe University Frankfurt am Main Coordinator of this site? Confirm its status | Frankfurt | Germany | Recruiting |
| Department for General and Visceral Surgery, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg Coordinator of this site? Confirm its status | Freiburg im Breisgau | Germany | Recruiting |
| JLU Gießen, Department for General, Visceral, Thoracic and Transplant Surgery Coordinator of this site? Confirm its status | Giessen | Germany | Recruiting |
| Clinic for General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Georg-August-University Coordinator of this site? Confirm its status | Göttingen | Germany | Recruiting |
| Clinic and Polyclinic for General Surgery, Department of Gastrointestinal, Thoracic and Vascular Surgery, University Greifswald, University Hospital Greifswald Coordinator of this site? Confirm its status | Greifswald | Germany | Recruiting |
| University Hospital and Polyclinic for Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale) Coordinator of this site? Confirm its status | Halle | Germany | Recruiting |
| Center for Surgical Medicine - Clinic and Polyclinic for General, Visceral and Thoracic Surgery, University Hospital Hamburg-Eppendorf Coordinator of this site? Confirm its status | Hamburg | Germany | Recruiting |
| Department of Liver, Bile Duct and Pancreas Surgery, University Department of surgery, Asklepios Klinik Barmbek Coordinator of this site? Confirm its status | Hamburg | Germany | Recruiting |
| Clinic for General, Visceral and Minimally Invasive Surgery, KRH Clinic Siloah, Hannover Coordinator of this site? Confirm its status | Hanover | Germany | Recruiting |
| Medizinische Hochschule Hannover, Department of General, Visceral and Transplant Surgery Coordinator of this site? Confirm its status | Hanover | Germany | Recruiting |
| Department of General, Visceral and Transplantation Surgery, University of Heidelberg Coordinator of this site? Confirm its status | Heidelberg | Germany | Recruiting |
| General Visceral and Vascular Surgery, Jena University Medical Center Coordinator of this site? Confirm its status | Jena | Germany | Recruiting |
| Clinic for Surgery, University Hospital Schleswig-Holstein Lübeck Campus Coordinator of this site? Confirm its status | Lübeck | Germany | Recruiting |
| University Department of General, Visceral, Vascular and Transplant Surgery, Faculty of Medicine, Otto von Guericke University Magdeburg Coordinator of this site? Confirm its status | Magdeburg | Germany | Recruiting |
| Clinic for General, Visceral and Transplantation Surgery, University Medical Center of the Johannes Gutenberg-University Mainz Coordinator of this site? Confirm its status | Mainz | Germany | Recruiting |
| Department of Surgery at the University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University Coordinator of this site? Confirm its status | Mannheim | Germany | Recruiting |
| Clinic for Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg Coordinator of this site? Confirm its status | Marburg | Germany | Recruiting |
| Department of Surgery, University Hospital rechts der Isar Coordinator of this site? Confirm its status | München | Germany | Recruiting |
| Department Hepato-Pancreato-Biliary Surgery, Barmherzige Brüder gGmbH of the Hospital Barmherzige Brüder Munich Coordinator of this site? Confirm its status | München | Germany | Recruiting |
| LMU Munich Hospital, Clinic for General, Visceral and Transplant Surgery Coordinator of this site? Confirm its status | Munich | Germany | Recruiting |
| Clinic for General, Visceral and Transplant Surgery, University of Münster Coordinator of this site? Confirm its status | Münster | Germany | Recruiting |
| University Hospital for General and Visceral Surgery, Oldenburg Hospital Coordinator of this site? Confirm its status | Oldenburg | Germany | Withdrawn |
| Department of General, Visceral and Transplant Surgery, University of Tübingen, Comprehensive Cancer Center Coordinator of this site? Confirm its status | Tübingen | Germany | Recruiting |
| Clinic for General and Visceral Surgery, Ulm University Medical Center Coordinator of this site? Confirm its status | Ulm | Germany | Recruiting |
| General and Visceral Surgery, Helios University Medical Center Wuppertal, University Witten/Herdecke Coordinator of this site? Confirm its status | Wuppertal | Germany | Recruiting |
| Department for General, Visceral, Transplant, Vascular and Pediatric Surgery, Julius-Maximilian-University Würzburg, University Hospital Würzburg Coordinator of this site? Confirm its status | Würzburg | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.