NCT04682223Recruiting
Telerehabilitation for Aphasia (TERRA)
Center for the Study of Aphasia Recovery (C-STAR): Telerehabilitation for Aphasia (TERRA)
Source: ClinicalTrials.gov · Last updated 2 Apr 2026
Brief summary (registry, in English)
Speech-language therapy is generally found to be helpful in the rehabilitation of aphasia. However, not all patients with aphasia have access to adequate treatment to maximize their recovery. The goal of this project is to compare the efficacy of telerehabilitation or Aphasia Remote Therapy (ART) to the more traditional In-Clinic Therapy (I-CT).
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 18 Dec 2020
- Start date
- 5 May 2021
- Primary completion date
- Jan 2027
- Lead sponsor
- University of South Carolina
- Diseases
- Stroke
- NCT number
- NCT04682223
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 5 May 2021 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participants must not have previous neurological disease affecting the brain (e.g. history of traumatic brain injury).
- Participants must not have severely limited speech production (severe unintelligibility) and/or auditory comprehension that interferes with adequate participation in the therapy provided (i.e., WAB-R Spontaneous Speech rating scale score of 0-1 or WAB-R Comprehension score of 0-1).
Other illness
- Participants must not have a history of stroke to the right hemisphere of the brain.
- Participants must not have a bilateral, cerebellar or brainstem stroke.
Other
- Participants must not have anything that makes them be 3T MRI incompatible
- Insufficient intelligible speech to provide accurate responses with discourse/naming.
Who the study is looking for
- Participants must have sustained a left hemisphere ischemic or hemorrhagic stroke at least 12 months prior to enrollment.
- Participants must primarily speak English for at least the past 20 years.
- Participants must be capable of giving informed consent or indicating another to provide informed consent.
- Participants must be between 21-80 years of age.
- Participants must be magnetic resonance imaging (MRI) compatible (e.g., no metal implants, not claustrophobic) on a 3-Tesla (3T) scanner.
Age in the registry: 21 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of South Carolina Aphasia Lab Coordinator of this site? Confirm its status | Columbia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.