NCT04685408Completed
A TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk Ugandans
A TargEted MAnageMent Intervention for Reducing Stroke Risk Factors in High Risk
Source: ClinicalTrials.gov · Last updated 7 Aug 2026
Brief summary (registry, in English)
The proposed 2-phase project will first refine the TargetEd MAnageMent (TEAM) intervention to ensure acceptability across a broad range of Ugandans at risk for stroke and then test the effects of TEAM in reducing stroke risk in a 3-site, prospective, 6-month randomized controlled trial (RCT).
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 276 (actual)
- First submitted
- 22 Dec 2020
- Start date
- 13 May 2022
- Primary completion date
- 6 Mar 2024
- Lead sponsor
- Case Western Reserve University
- Diseases
- Stroke
- NCT number
- NCT04685408
What you commit to
- Study type: Interventional
- Participants enrolled: 276
- From 13 May 2022 to the primary completion date, 6 Mar 2024
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Individuals who have sickle-cell disease
- Individuals with dementia
Other
- Individuals who are unable or unwilling to provide written informed consent
- Females who are pregnant or lactating
Who the study is looking for
- Age range: ≥ 18 years
- At risk for stroke defined by the following:
- High systolic BP defined as ≥ 140 mmHg assessed on at least 2 occasions at least 3 days apart and either criterion b or c as noted below:
- At least 1 other modifiable stroke risk factor including: diabetes, hyperlipidemia, obesity, smoking, problem alcohol use or sedentary lifestyle. Problem alcohol use for screening purposes will be assessed with questions on frequency, type of alcohol and quantity consumed. Participants will be classified as engaging in potential problem alcohol use if they exceed the recommended level for safe alcohol intake i.e. more than 3 drinks on average every time they drink, or if they undertook binge drinking (i.e. more than 3 drinks on one occasion in the one month preceding the evaluation).
- History of stroke or transient ischemic attack within the past 5 years
- Able to participate in group sessions
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mulago Hospital Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
| Nsambya Hospital Coordinator of this site? Confirm its status | Kampala | Uganda | Unknown status |
| Mbarara Regional Referral Hospital Coordinator of this site? Confirm its status | Mbarara | Uganda | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.