NCT04687904Completed
Mindfulness Meditation for Epilepsy
Mindfulness Meditation for Epilepsy: Effect of Mindfulness Meditation Practice on Quality of Life and EEG Activity in Refractory Epilepsy
Source: ClinicalTrials.gov · Last updated 17 Feb 2026
Brief summary (registry, in English)
In one-third of epileptic patients treated in France, seizures persist despite drug treatment. These so-called "refractory" epilepsies are among the most severe. Only a minority of patients with refractory epilepsy can undergo surgery. The other options available are based on brain or vagus nerve stimulation interventions which clinical effectiveness is still being studied. Alternative therapies are needed both to decrease the frequency of patients' seizures and to improve their quality of life. The practice of mindfulness meditation has recently been included in the recommendations of the International League Against Epilepsy in order to alleviate anxiety or depression comorbid symptoms. This study falls within this framework by targeting two aspects of the pathology.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 37 (actual)
- First submitted
- 18 Dec 2020
- Start date
- 14 Jan 2021
- Primary completion date
- 6 Jun 2024
- Lead sponsor
- Rennes University Hospital
- Diseases
- Epilepsy
- NCT number
- NCT04687904
What you commit to
- Study type: Interventional
- Participants enrolled: 37
- From 14 Jan 2021 to the primary completion date, 6 Jun 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- For patients :
- Alcohol Addiction Disorders (assessed by the Mini-International Neuropsychiatric Interview (MINI) scale) ;
- Patients with psychogenic crises;
- Treatment with antidepressants;
- Simultaneous participation in other research that may interfere with the protocol;
- Persons of legal age subject to legal protection (safeguard of justice, curatorship, guardianship), persons deprived of liberty.
Age
- For healthy subjects :
- Psychiatric pathology and/or alcohol addiction disorders (evaluated by the MINI scale) ;
- Simultaneous participation in other research that may interfere with the protocol;
- Persons of legal age subject to legal protection (protection of justice, guardianship, trusteeship), persons deprived of liberty.
Who the study is looking for
- For patients :
- Patients over 16 years of age;
- Epilepsy refractory to drug treatment according to the consensus criteria of the International League Against Epilepsy ;
- Affiliated with a health insurance plan;
- Free, informed and written consent signed by the patient, and parents for patients under the age of 18.
- For healthy subjects :
- Healthy subjects 16 years of age and older;
- Affiliated with a health insurance plan;
- Free, informed and written consent signed by the volunteer, or parents, for volunteers under the age of 18.
Age in the registry: 16 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Hospitalier Universitaire Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.