NCT04694534Recruiting
Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients
e-SEP Cognition: Effectiveness of a Remediation Program Via a "Serious Game" on the Cognitive Functions of Multiple Sclerosis Patients: Controlled, Randomized, Multicentric Trial
Source: ClinicalTrials.gov · Last updated 4 Sept 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 16 Dec 2020
- Start date
- Oct 2021
- Primary completion date
- Apr 2026
- Lead sponsor
- Lille Catholic University
- Diseases
- Multiple sclerosis
- NCT number
- NCT04694534
What you commit to
- Study type: Interventional
- Planned participants: 150
- From Oct 2021 to the primary completion date, Apr 2026
- 6 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
- Patient with severe anxiodepressive syndrome (BDI\> 27)
Other
- Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
- Neuropsychological care
- Inability to receive oral and written information
- Inability to use the software (due in particular to motor and / or sensory difficulties),
- Participation in an interventional study on cognitive functions
- Patient under legal protection, guardianship or curatorship
- Pregnant or breastfeeding women
Who the study is looking for
- Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
- Age between ≥ 18 and ≤ 65 years old
- Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
- Have not had a definite relapse for at least 6 weeks
- Be at least 4 weeks away from a corticosteroid bolus
- Lack of neuroleptic treatment
- Patient with an Internet connection
- Signed informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (6)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CH Arras Coordinator of this site? Confirm its status | Arras | France | Recruiting |
| CH Lens Coordinator of this site? Confirm its status | Lens | France | Recruiting |
| CHRU Coordinator of this site? Confirm its status | Lille | France | Recruiting |
| Saint Vincent hospital Coordinator of this site? Confirm its status | Lille | France | Recruiting |
| Saint-Philibert hospital Coordinator of this site? Confirm its status | Lomme | France | Recruiting |
| Charles Nicolle Hospital Coordinator of this site? Confirm its status | Rouen | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.