NCT04700722Completed
Synuclein-One Study
Cutaneous Phosphorlyated α-synuclein Detection as a Biomarker of Synucleinopathy
Source: ClinicalTrials.gov · Last updated 3 Jan 2024 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The Synuclein-One Study will be evaluating α-synuclein in patients with Parkinson's disease, Multiple System Atrophy, Dementia with Lewy bodies and Pure Autonomic Failure. Using a simple diagnostic test will improve clinical accuracy in diagnosing, earlier diagnosis, and distinguish between neurodegenerative diseases.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 428 (actual)
- First submitted
- 6 Jan 2021
- Start date
- 4 Jan 2021
- Primary completion date
- 14 Dec 2022
- Lead sponsor
- CND Life Sciences
- Diseases
- Lewy body dementia, Parkinson disease
- NCT number
- NCT04700722
What you commit to
- Study type: Observational
- Participants enrolled: 428
- From 4 Jan 2021 to the primary completion date, 14 Dec 2022
- 23 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Clinical evidence of severe vascular disease (history of ulceration, poor wound healing, vascular claudication)
- Clinically active coronary artery or cerebrovascular disease
- History of allergic reaction to local anesthesia for skin biopsies
- Significantly impaired wound healing or history of scarring or keloid formation
- Healthy individuals or individuals with synucleinopathy is disease may be explained by other causes: recent history of encephalitis, Cortical dementia of Alzheimer's type, Whipple's disease, toxin exposure, repeated head injury and stepwise disease progression suggestive of vascular etiology
Other
- Current smoker or alcoholism
- Use of blood thinners (aspirin or Plavix alone is allowed)
Who the study is looking for
- Male and female between 40-99 years of age
- Prior clinical diagnosis of Parkinson's disease, Multiple System Atrophy, Dementia with Lewy bodies or Pure Autonomic Failure
- Health Subjects, no history of clinical or symptoms suggestive with synucleinopathy
Age in the registry: 40 years to 99 years · Sex: All
Sites (23)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aventura Neurology Coordinator of this site? Confirm its status | Aventura | United States | Unknown status |
| Parkinson's Disease and Movement Disorders Center of Boca Raton Coordinator of this site? Confirm its status | Boca Raton | United States | Unknown status |
| Beth Israel Lahey Health Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Boston Medical Center Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| The Neuro Center Coordinator of this site? Confirm its status | Carlsbad | United States | Unknown status |
| MD First Research Coordinator of this site? Confirm its status | Chandler | United States | Unknown status |
| UTSouthwestern Coordinator of this site? Confirm its status | Dallas | United States | Unknown status |
| Duke University Medical Center Coordinator of this site? Confirm its status | Durham | United States | Unknown status |
| Rocky Mountain Movement Disorders Center, PC Coordinator of this site? Confirm its status | Englewood | United States | Unknown status |
| Northshore University Health System Coordinator of this site? Confirm its status | Evanston | United States | Unknown status |
| UF College of Medicine Coordinator of this site? Confirm its status | Gainesville | United States | Unknown status |
| Texas Movement Disorders Specialists Coordinator of this site? Confirm its status | Georgetown | United States | Unknown status |
| Evergreen Health Coordinator of this site? Confirm its status | Kirkland | United States | Unknown status |
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Unknown status |
| NYU Medical Center Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| SouthShore Neurologic Coordinator of this site? Confirm its status | Patchogue | United States | Unknown status |
| CND Life Sciences Coordinator of this site? Confirm its status | Phoenix | United States | Unknown status |
| Parkinson's Disease Treatment Center SWFL Coordinator of this site? Confirm its status | Port Charlotte | United States | Unknown status |
| Providence Brain & Spine Institute Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
| Mayo Clinic Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
| Providence St. John's Health Coordinator of this site? Confirm its status | Santa Monica | United States | Unknown status |
| Movement Disorders Center of Arizona Coordinator of this site? Confirm its status | Scottsdale | United States | Unknown status |
| Swedish Neuroscience Research Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.