NCT04704115Recruiting
The Therapy of Large Endometrioma
Evaluate the Therapy of Large Ovarian Endometrioma
Source: ClinicalTrials.gov · Last updated 23 Dec 2025
Brief summary (registry, in English)
Endometrioma's prevalence is between 23 and 55%. It causes pelvic pain, decrease fertility and ovarian reserve. Currently, there's no recommendation about large endometrioma's treatment and there's no information on the best treatment to limit recurrences, preserve fertility and ovarian reserve. In Lille university hospital, simple laparoscopic drainage associated with hormonal therapy is practiced to reduce the risk of cystectomy. This protocol will be evaluated with an observational and prospective study, including women of childbearing age having endometrioma measuring 6 cm or above. The aim of this study is to assess if cyst drainage associated with GnRH agonist, could decrease endometrioma recurrences, deleterious effect on ovarian reserve and evaluate impact on anti-mullerian hormone
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 62 (estimated)
- First submitted
- 7 Jan 2021
- Start date
- 21 Jan 2021
- Primary completion date
- Dec 2026
- Lead sponsor
- University Hospital, Lille
- Diseases
- Endometriosis
- NCT number
- NCT04704115
What you commit to
- Study type: Observational
- Planned participants: 62
- From 21 Jan 2021 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Cyst with radiographic or macroscopic in laparoscopy atypia
- Pregnancy
- Patient with contraindication to GnRH agonist (Enantone® 3,75 mg et Decapeptyl® 3 mg)
- Patient with contraindication to laparoscopy
- Patient with contraindication to general anesthesia
- Subject refusing to participate in the study
Who the study is looking for
- Endometrioma size ≥ 6cm determined by MRI or ultrasonography
- Women with isolated endometrioma or other extraovarian endometriosis: peritoneal, infiltrating endometriotic lesions and adenomyosis.
- Cyst single or bilateral
Age in the registry: 18 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hop Jeanne de Flandre Chu Lille Coordinator of this site? Confirm its status | Lisle-sur-Tarn | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.