NCT04706234Recruiting
Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
Prospective Observational Study for the Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
Source: ClinicalTrials.gov · Last updated 9 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 350 (estimated)
- First submitted
- 9 Jan 2021
- Start date
- 1 Sept 2017
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Kliniken Beelitz GmbH
- Diseases
- Parkinson disease
- NCT number
- NCT04706234
What you commit to
- Study type: Observational
- Planned participants: 350
- From 1 Sept 2017 to the primary completion date, 31 Dec 2027
- 16 sites in 8 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- \- Patients who do not sign the consent form
Who the study is looking for
- diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or
- diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or
- diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015)
- Hoehn and Yahr Stage within the range of I-V or
- diagnosis of motor neurone disease or
- diagnosis of a neurodegenerative disease other than specified above
- AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019).
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Neurology and Department of ENT, Medical University Innsbruck Coordinator of this site? Confirm its status | Innsbruck | Austria | Recruiting |
| Movement Disorders Hospital - Kliniken Beelitz Coordinator of this site? Confirm its status | Beelitz-Heilstätten | Germany | Recruiting |
| Department of Neurology, University Hospital Carl Gustav Carus Coordinator of this site? Confirm its status | Dresden | Germany | Recruiting |
| Asklepios Klinik Barmbek Coordinator of this site? Confirm its status | Hamburg | Germany | Recruiting |
| Department of Neurology Asklepios Klinik Barmbek Coordinator of this site? Confirm its status | Hamburg | Germany | Recruiting |
| Department of Neurology, Medical School Hannover Coordinator of this site? Confirm its status | Hanover | Germany | Recruiting |
| Department of Neurology, University Hospital Münster Coordinator of this site? Confirm its status | Münster | Germany | Recruiting |
| Asklepios Fachklinikum Stadtroda Coordinator of this site? Confirm its status | Stadtroda | Germany | Recruiting |
| Department of Neueology Asklepios Klinik Stadtroda Coordinator of this site? Confirm its status | Stadtroda | Germany | Recruiting |
| Department of Neurology, Medical University of Ulm Coordinator of this site? Confirm its status | Ulm | Germany | Recruiting |
| Unidad de Parkinson y Trastornos del Movimiento Instituto Clínic de Neurociencias, Hospital Clinic de Barcelona Coordinator of this site? Confirm its status | Barcelona | Spain | Recruiting |
| Department of Neurology, Movement Disorders Unit, Medical Center Tel Aviv Coordinator of this site? Confirm its status | Tel Aviv | Israel | Recruiting |
| IRCCS Istituto delle Scienze Neurologiche, Azienda USL di Bologna Coordinator of this site? Confirm its status | Bologna | Italy | Recruiting |
| Department of Neurology, Gifu University Graduate School of Medicine Coordinator of this site? Confirm its status | Gifu | Japan | Recruiting |
| Department of Neurology SNUCM Coordinator of this site? Confirm its status | Seoul | South Korea | Recruiting |
| Department of Neurology, Medical University Warsaw Coordinator of this site? Confirm its status | Warsaw | Poland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.