NCT04706676Active, not recruiting
Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer
Integrative Neuromuscular Training in Adolescents and Children Treated for Cancer- a Multicenter Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 11 Jun 2025
Brief summary (registry, in English)
The INTERACT study is a nation-wide, population-based randomized controlled trial to investigate the effects of 6-month integrative neuromuscular training during anti-cancer treatment on lower body muscle strength, metabolic syndrome, various measures of physical function, physical activity, days of hospitalization, health-related quality of life and health behavior in children and adolescents with cancer. The increased insight derived from this study will impact the development of pediatric exercise oncology and be of high relevance to a broad group of children and adolescents with severe chronic illness. The study is based on the overarching hypothesis, that structured integrative neuromuscular training initiated immediately after diagnosis will be effective in preventing deficits in neuromuscular function, limit long-term cardio-metabolic morbidity and found long-standing improvements in physical activity behavior. To maintain adherence and motivation throughout a 6-month training intervention, weekly supervision of the training is needed. For this study, it is hypothesized that a supervised exercise intervention, in addition to a motivational counseling intervention and usual care, will improve muscle strength compared with unsupervised home-based training (active controls).
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 132 (estimated)
- First submitted
- 5 Jan 2021
- Start date
- 26 Jan 2021
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- Childhood cancers
- NCT number
- NCT04706676
What you commit to
- Study type: Interventional
- Planned participants: 132
- From 26 Jan 2021 to the primary completion date, 31 Oct 2026
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- terminal illness
Other
- Severe mental and/or physical disability, i.e. participants where all types of physical training and testing of physical function are contraindicated
- unable to communicate in Danish
Who the study is looking for
- All malign and benign disorders treated with chemotherapy and/or irradiation
Age in the registry: 6 years to 18 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
| Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| Odense University Hospital Coordinator of this site? Confirm its status | Odense | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.