NCT04708418Active, not recruitingPhase 2
A Study Evaluating Whether Pembrolizumab Alone or in Combination With CMP-001 Improves Efficacy of Treatment in Patients With Operable Melanoma
Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination With CMP-001 in Patients With Operable Melanoma: Efficacy and Biomarker Study
Source: ClinicalTrials.gov · Last updated 29 Sept 2026
Brief summary (registry, in English)
This phase II trial studies the effect of pembrolizumab alone or in combination with CMP-001 in treating patients with melanoma that can be treated by surgery (operable). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Immunotherapy with CMP-001 may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. The addition of CMP-001 to pembrolizumab could improve the ability of the immune system to shrink tumors and to prevent them from returning.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 13 Jan 2021
- Start date
- 15 Oct 2021
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- National Cancer Institute (NCI)
- Diseases
- Melanoma
- NCT number
- NCT04708418
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 60
- From 15 Oct 2021 to the primary completion date, 31 Dec 2026
- 187 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Patient must be \>= 18 years of age
- Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
- Patient must have a histologic diagnosis of melanoma belonging to the following American Joint Committee on Cancer (AJCC) 8th edition TNM stages:
- T0, Tx or T1-4; and
- N1b, N2b, N2c, N3b or N3c
- Patients may have a presentation with primary melanoma with concurrent regional nodal and/or in-transit metastasis; or patients may have a history of primary melanoma or unknown primary melanoma presenting with clinically detected regional nodal and/or in-transit recurrence; and may belong to any of the following groups:
- Primary cutaneous melanoma with clinically apparent regional lymph node metastases and/or in-transit metastases
- Clinically detected recurrent melanoma at the proximal regional lymph node(s) basin
- Primary cutaneous melanoma with concurrent nodal disease involving a single (or multiple) regional nodal group(s) if considered potentially surgically resectable at baseline
- Clinically detected nodal melanoma (if single site) arising from an unknown primary
- In-transit cutaneous metastases with or without regional lymph node involvement permitted if considered potentially surgically resectable at baseline
- NOTE: Patients with mucosal and/or uveal melanoma are not eligible for the study
- Patient must be a candidate for definitive surgery and have met with the treating surgical oncologist prior to randomization
- Patient must not have received any live vaccine within 30 days prior to randomization and while participating in the study. Live vaccines include, but are not limited to, the following: measles, mumps, rubella, chicken pox, yellow fever, rabies, Bacillus Calmette-Guerin (BCG), and typhoid (oral) vaccine. Patients are permitted to receive inactivated vaccines and any non-live vaccines including those for the seasonal influenza and COVID-19 (Note: intranasal influenza vaccines, such as Flu-Mist \[registered trademark\] are live attenuated vaccines and are not allowed). If possible, it is recommended to separate study drug administration from vaccine administration by about a week (primarily, in order to minimize an overlap of adverse events)
- Patient must have the presence of injectable and measurable disease based on Response Evaluation Criteria in Solid Tumors (RECIST) 1.1, documented by scans obtained within 4 weeks prior to randomization
- NOTE: Injectable disease is defined as an accessible lesion in the skin, subcutaneous tissue or lymph nodes (LN) close to the skin and palpable by physical examination or approachable with ultrasound guidance
- Absolute neutrophil count (ANC) \>= 1,500 /mcL (obtained within 4 weeks prior to randomization)
- Hemoglobin (Hgb) \>= 9 g/dL or \>= 5.6 mmol/L (obtained within 4 weeks prior to randomization)
- Platelets \>= 100,000 / mcL (obtained within 4 weeks prior to randomization)
- Serum creatinine =\< 1.5 x institutional upper limit of normal (ULN) or measured or calculated creatinine clearance \> 60 mL/min (glomerular filtration rate \[GFR\] can also be used in place of creatinine or creatinine clearance \[CrCl\] for patients with creatinine levels \> 1.5 x institutional ULN) (obtained within 4 weeks prior to randomization)
- Serum total bilirubin =\< 1.5 x institutional ULN; for total bilirubin level \> 1.5 x ULN but =\< 3 x ULN, the direct bilirubin must be =\< the institutional ULN (obtained within 4 weeks prior to randomization)
- Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase \[SGOT\]) and alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase \[SGPT\]) =\< 2.5 x institutional ULN (obtained within 4 weeks prior to randomization)
- International normalized ratio (INR) or prothrombin time (PT) =\< 1.5 x institutional ULN unless patient is receiving anticoagulant therapy as long as PT or partial thromboplastin time (PTT) is within therapeutic range of intended use of anticoagulants (obtained within 4 weeks prior to randomization)
- Activated partial thromboplastin time (aPTT) =\< 1.5 x institutional ULN unless patient is receiving anticoagulant therapy as long as PT or PTT is within therapeutic range of intended use of anticoagulants (obtained within 4 weeks prior to randomization)
- Patients must not be pregnant or breast-feeding due to the potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used. All patients of childbearing potential must have a blood test or urine study within 14 days prior to randomization to rule out pregnancy. A urine or serum pregnancy test must be repeated within 72 hours prior to receiving the first dose of pembrolizumab if the test done for eligibility/randomization is done outside of this 72 hour window. If the urine test is positive or cannot be confirmed as negative, a serum pregnancy test will be required. A patient of childbearing potential is defined as anyone, regardless of whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
- Patients must not expect to conceive or father children by using accepted and effective method(s) of contraception or abstaining from sexual intercourse from time of randomization, while on study treatment, and continue for 26 weeks after the last dose of protocol treatment
- Patient must have the ability to understand and the willingness to sign a written informed consent document. Patients with impaired decision-making capacity (IDMC) who have a legally authorized representative (LAR) or caregiver and/or family member available will also be considered eligible
- Patient must not have received prior systemic therapy for melanoma including systemic therapy with an anti-PD-1, anti-PD-L1, anti-CTLA-4, BRAF/MEK inhibitor combination and/or TLR-9 agonist
- Patient must not have a diagnosis of immunodeficiency or be receiving systemic steroid therapy or any other form of immunosuppressive therapy within 7 days prior to randomization, except as noted here
- Patients who are currently receiving steroids at a dose of prednisone =\< 5 mg daily (or equivalent) are permitted to enroll
- Patients who require topical, ophthalmologic and inhalational steroids are permitted to enroll
- Patients with hypothyroidism who are stable on hormone replacement are permitted to enroll
- Patients who require active immunosuppression with corticosteroids at a dose of prednisone \> 5 mg daily (or equivalent) for any reason are ineligible
- Patients with adrenal insufficiency are ineligible
- Patients who have developed autoimmune disorders of grade 4 while on prior immunotherapy are not permitted to enroll on this study. Patients who developed autoimmune disorders of grade =\< 3 may enroll if the disorder has resolved to grade =\< 1 and the patient has been off systemic corticosteroids at doses \> 5 mg for at least 2 weeks prior to randomization
- Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months prior to randomization are eligible for this trial
- For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated
- Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load
- Patients with a history of brain metastases are not eligible for this study as they do not meet the eligibility staging criteria
- Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial
- Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better
- Patient must not have had an allogeneic tissue/solid organ transplant
- Patient must not have a history of (non-infectious) pneumonitis that required steroids or current pneumonitis
- Patient must not have severe hypersensitivity (\>= grade 3) to pembrolizumab and/or any of its excipients
- Patient must not have an active infection requiring systemic therapy
- Patient must not have a known psychiatric or substance abuse disorder that would interfere with the patient's ability to cooperate with the requirements of the study
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (187)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Providence Regional Cancer System-Aberdeen Coordinator of this site? Confirm its status | Aberdeen | United States | Unknown status |
| Avera Cancer Institute-Aberdeen Coordinator of this site? Confirm its status | Aberdeen | United States | Unknown status |
| Saint Luke's Cancer Center - Allentown Coordinator of this site? Confirm its status | Allentown | United States | Unknown status |
| Mary Greeley Medical Center Coordinator of this site? Confirm its status | Ames | United States | Unknown status |
| McFarland Clinic - Ames Coordinator of this site? Confirm its status | Ames | United States | Unknown status |
| Alaska Breast Care and Surgery LLC Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Alaska Oncology and Hematology LLC Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Providence Alaska Medical Center Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Alaska Women's Cancer Care Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Anchorage Oncology Centre Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Katmai Oncology Group Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Anchorage Associates in Radiation Medicine Coordinator of this site? Confirm its status | Anchorage | United States | Unknown status |
| Rocky Mountain Cancer Centers-Aurora Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
| The Medical Center of Aurora Coordinator of this site? Confirm its status | Aurora | United States | Unknown status |
| UM Sylvester Comprehensive Cancer Center at Aventura Coordinator of this site? Confirm its status | Aventura | United States | Unknown status |
| Mercy Oncology and Hematology - Clayton-Clarkson Coordinator of this site? Confirm its status | Ballwin | United States | Unknown status |
| Mary Bird Perkins Cancer Center Coordinator of this site? Confirm its status | Baton Rouge | United States | Unknown status |
| Louisiana Hematology Oncology Associates LLC Coordinator of this site? Confirm its status | Baton Rouge | United States | Unknown status |
| Bronson Battle Creek Coordinator of this site? Confirm its status | Battle Creek | United States | Unknown status |
| Indu and Raj Soin Medical Center Coordinator of this site? Confirm its status | Beavercreek | United States | Unknown status |
| PeaceHealth Saint Joseph Medical Center Coordinator of this site? Confirm its status | Bellingham | United States | Unknown status |
| Saint Charles Health System Coordinator of this site? Confirm its status | Bend | United States | Unknown status |
| Central Vermont Medical Center/National Life Cancer Treatment Coordinator of this site? Confirm its status | Berlin Corners | United States | Unknown status |
| Saint Luke's University Hospital-Bethlehem Campus Coordinator of this site? Confirm its status | Bethlehem | United States | Unknown status |
| Illinois CancerCare-Bloomington Coordinator of this site? Confirm its status | Bloomington | United States | Unknown status |
| Saint Luke's Cancer Institute - Boise Coordinator of this site? Confirm its status | Boise | United States | Unknown status |
| Central Care Cancer Center - Bolivar Coordinator of this site? Confirm its status | Bolivar | United States | Unknown status |
| McFarland Clinic - Boone Coordinator of this site? Confirm its status | Boone | United States | Unknown status |
| Rocky Mountain Cancer Centers-Boulder Coordinator of this site? Confirm its status | Boulder | United States | Unknown status |
| Providence Saint Joseph Medical Center/Disney Family Cancer Center Coordinator of this site? Confirm its status | Burbank | United States | Unknown status |
| University of Vermont Medical Center Coordinator of this site? Confirm its status | Burlington | United States | Unknown status |
| Illinois CancerCare-Canton Coordinator of this site? Confirm its status | Canton | United States | Unknown status |
| Saint Francis Medical Center Coordinator of this site? Confirm its status | Cape Girardeau | United States | Unknown status |
| Mercy Cancer Center - Cape Girardeau Coordinator of this site? Confirm its status | Cape Girardeau | United States | Unknown status |
| Memorial Hospital of Carbondale Coordinator of this site? Confirm its status | Carbondale | United States | Unknown status |
| SIH Cancer Institute Coordinator of this site? Confirm its status | Carterville | United States | Unknown status |
| Illinois CancerCare-Carthage Coordinator of this site? Confirm its status | Carthage | United States | Unknown status |
| Rocky Mountain Cancer Centers - Centennial Coordinator of this site? Confirm its status | Centennial | United States | Unknown status |
| Miami Valley Hospital South Coordinator of this site? Confirm its status | Centerville | United States | Unknown status |
| Dayton Physicians LLC-Miami Valley South Coordinator of this site? Confirm its status | Centerville | United States | Unknown status |
| Centralia Oncology Clinic Coordinator of this site? Confirm its status | Centralia | United States | Unknown status |
| Providence Regional Cancer System-Centralia Coordinator of this site? Confirm its status | Centralia | United States | Unknown status |
| University of Virginia Cancer Center Coordinator of this site? Confirm its status | Charlottesville | United States | Unknown status |
| University of Illinois Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| Oncology Hematology Care Inc-Kenwood Coordinator of this site? Confirm its status | Cincinnati | United States | Unknown status |
| Clackamas Radiation Oncology Center Coordinator of this site? Confirm its status | Clackamas | United States | Unknown status |
| Providence Cancer Institute Clackamas Clinic Coordinator of this site? Confirm its status | Clackamas | United States | Unknown status |
| Bay Area Hospital Coordinator of this site? Confirm its status | Coos Bay | United States | Unknown status |
| UM Sylvester Comprehensive Cancer Center at Coral Gables Coordinator of this site? Confirm its status | Coral Gables | United States | Unknown status |
| Miami Valley Hospital North Coordinator of this site? Confirm its status | Dayton | United States | Unknown status |
| Miami Valley Hospital Coordinator of this site? Confirm its status | Dayton | United States | Unknown status |
| Dayton Physician LLC - Englewood Coordinator of this site? Confirm its status | Dayton | United States | Unknown status |
| Cancer Care Specialists of Illinois - Decatur Coordinator of this site? Confirm its status | Decatur | United States | Unknown status |
| Decatur Memorial Hospital Coordinator of this site? Confirm its status | Decatur | United States | Unknown status |
| UM Sylvester Comprehensive Cancer Center at Deerfield Beach Coordinator of this site? Confirm its status | Deerfield Beach | United States | Unknown status |
| Rocky Mountain Cancer Centers-Midtown Coordinator of this site? Confirm its status | Denver | United States | Unknown status |
| Rocky Mountain Cancer Centers-Rose Coordinator of this site? Confirm its status | Denver | United States | Unknown status |
| Presbyterian - Saint Lukes Medical Center - Health One Coordinator of this site? Confirm its status | Denver | United States | Unknown status |
| Illinois CancerCare-Dixon Coordinator of this site? Confirm its status | Dixon | United States | Unknown status |
| Epic Care-Dublin Coordinator of this site? Confirm its status | Dublin | United States | Unknown status |
| Saint Luke's Hospital-Anderson Campus Coordinator of this site? Confirm its status | Easton | United States | Unknown status |
| Marshfield Medical Center-EC Cancer Center Coordinator of this site? Confirm its status | Eau Claire | United States | Unknown status |
| Swedish Cancer Institute-Edmonds Coordinator of this site? Confirm its status | Edmonds | United States | Unknown status |
| Crossroads Cancer Center Coordinator of this site? Confirm its status | Effingham | United States | Unknown status |
| Bay Area Breast Surgeons Inc Coordinator of this site? Confirm its status | Emeryville | United States | Unknown status |
| Epic Care Partners in Cancer Care Coordinator of this site? Confirm its status | Emeryville | United States | Unknown status |
| Rocky Mountain Cancer Centers - Swedish Coordinator of this site? Confirm its status | Englewood | United States | Unknown status |
| Swedish Medical Center Coordinator of this site? Confirm its status | Englewood | United States | Unknown status |
| The Melanoma and Skin Cancer Institute Coordinator of this site? Confirm its status | Englewood | United States | Unknown status |
| Mountain Blue Cancer Care Center - Swedish Coordinator of this site? Confirm its status | Englewood | United States | Unknown status |
| Illinois CancerCare-Eureka Coordinator of this site? Confirm its status | Eureka | United States | Unknown status |
| Providence Regional Cancer Partnership Coordinator of this site? Confirm its status | Everett | United States | Unknown status |
| Fairbanks Memorial Hospital Coordinator of this site? Confirm its status | Fairbanks | United States | Unknown status |
| Parkland Health Center - Farmington Coordinator of this site? Confirm its status | Farmington | United States | Unknown status |
| Blanchard Valley Hospital Coordinator of this site? Confirm its status | Findlay | United States | Unknown status |
| Armes Family Cancer Center Coordinator of this site? Confirm its status | Findlay | United States | Unknown status |
| Orion Cancer Care Coordinator of this site? Confirm its status | Findlay | United States | Unknown status |
| McFarland Clinic - Trinity Cancer Center Coordinator of this site? Confirm its status | Fort Dodge | United States | Unknown status |
| Mercy Hospital Fort Smith Coordinator of this site? Confirm its status | Fort Smith | United States | Unknown status |
| Atrium Medical Center-Middletown Regional Hospital Coordinator of this site? Confirm its status | Franklin | United States | Unknown status |
| Dayton Physicians LLC-Atrium Coordinator of this site? Confirm its status | Franklin | United States | Unknown status |
| Saint Luke's Cancer Institute - Fruitland Coordinator of this site? Confirm its status | Fruitland | United States | Unknown status |
| Western Illinois Cancer Treatment Center Coordinator of this site? Confirm its status | Galesburg | United States | Unknown status |
| Illinois CancerCare-Galesburg Coordinator of this site? Confirm its status | Galesburg | United States | Unknown status |
| Central Care Cancer Center - Garden City Coordinator of this site? Confirm its status | Garden City | United States | Unknown status |
| Corewell Health Grand Rapids Hospitals - Butterworth Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Unknown status |
| Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Unknown status |
| Trinity Health Grand Rapids Hospital Coordinator of this site? Confirm its status | Grand Rapids | United States | Unknown status |
| Central Care Cancer Center - Great Bend Coordinator of this site? Confirm its status | Great Bend | United States | Unknown status |
| Banner North Colorado Medical Center Coordinator of this site? Confirm its status | Greeley | United States | Unknown status |
| Dayton Physicians LLC-Wayne Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
| Wayne Hospital Coordinator of this site? Confirm its status | Greenville | United States | Unknown status |
| Terrebonne General Medical Center Coordinator of this site? Confirm its status | Houma | United States | Unknown status |
| Swedish Cancer Institute-Issaquah Coordinator of this site? Confirm its status | Issaquah | United States | Unknown status |
| McFarland Clinic - Jefferson Coordinator of this site? Confirm its status | Jefferson | United States | Unknown status |
| MU Health Care Goldschmidt Cancer Center Coordinator of this site? Confirm its status | Jefferson City | United States | Unknown status |
| Freeman Health System Coordinator of this site? Confirm its status | Joplin | United States | Unknown status |
| Mercy Hospital Joplin Coordinator of this site? Confirm its status | Joplin | United States | Unknown status |
| Beacon Kalamazoo Coordinator of this site? Confirm its status | Kalamazoo | United States | Unknown status |
| West Michigan Cancer Center Coordinator of this site? Confirm its status | Kalamazoo | United States | Unknown status |
| Beacon Kalamazoo Cancer Center Coordinator of this site? Confirm its status | Kalamazoo | United States | Unknown status |
| Bronson Methodist Hospital Coordinator of this site? Confirm its status | Kalamazoo | United States | Unknown status |
| Kadlec Clinic Hematology and Oncology Coordinator of this site? Confirm its status | Kennewick | United States | Unknown status |
| Kettering Medical Center Coordinator of this site? Confirm its status | Kettering | United States | Unknown status |
| Greater Dayton Cancer Center Coordinator of this site? Confirm its status | Kettering | United States | Unknown status |
| Illinois CancerCare-Kewanee Clinic Coordinator of this site? Confirm its status | Kewanee | United States | Unknown status |
| Providence Regional Cancer System-Lacey Coordinator of this site? Confirm its status | Lacey | United States | Unknown status |
| Rocky Mountain Cancer Centers-Littleton Coordinator of this site? Confirm its status | Littleton | United States | Unknown status |
| Sky Ridge Medical Center Coordinator of this site? Confirm its status | Lone Tree | United States | Unknown status |
| Rocky Mountain Cancer Centers-Sky Ridge Coordinator of this site? Confirm its status | Lone Tree | United States | Unknown status |
| PeaceHealth Saint John Medical Center Coordinator of this site? Confirm its status | Longview | United States | Unknown status |
| Banner North Colorado Medical Center - Loveland Campus Coordinator of this site? Confirm its status | Loveland | United States | Unknown status |
| Illinois CancerCare-Macomb Coordinator of this site? Confirm its status | Macomb | United States | Unknown status |
| McFarland Clinic - Marshalltown Coordinator of this site? Confirm its status | Marshalltown | United States | Unknown status |
| Marshfield Medical Center-Marshfield Coordinator of this site? Confirm its status | Marshfield | United States | Unknown status |
| Contra Costa Regional Medical Center Coordinator of this site? Confirm its status | Martinez | United States | Unknown status |
| Saint Luke's Cancer Institute - Meridian Coordinator of this site? Confirm its status | Meridian | United States | Unknown status |
| University of Miami Miller School of Medicine-Sylvester Cancer Center Coordinator of this site? Confirm its status | Miami | United States | Unknown status |
| Medical College of Wisconsin Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
| Marshfield Medical Center - Minocqua Coordinator of this site? Confirm its status | Minocqua | United States | Unknown status |
| Saint Patrick Hospital - Community Hospital Coordinator of this site? Confirm its status | Missoula | United States | Unknown status |
| SSM Health Good Samaritan Coordinator of this site? Confirm its status | Mount Vernon | United States | Unknown status |
| Trinity Health Muskegon Hospital Coordinator of this site? Confirm its status | Muskegon | United States | Unknown status |
| Saint Luke's Cancer Institute - Nampa Coordinator of this site? Confirm its status | Nampa | United States | Unknown status |
| Providence Newberg Medical Center Coordinator of this site? Confirm its status | Newberg | United States | Unknown status |
| Corewell Health Lakeland Hospitals - Niles Hospital Coordinator of this site? Confirm its status | Niles | United States | Unknown status |
| Cancer and Hematology Centers of Western Michigan - Norton Shores Coordinator of this site? Confirm its status | Norton Shores | United States | Unknown status |
| Alta Bates Summit Medical Center - Summit Campus Coordinator of this site? Confirm its status | Oakland | United States | Unknown status |
| Bay Area Tumor Institute Coordinator of this site? Confirm its status | Oakland | United States | Unknown status |
| Cancer Care Center of O'Fallon Coordinator of this site? Confirm its status | O'Fallon | United States | Unknown status |
| Mercy Hospital Oklahoma City Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| Saint Joseph Hospital - Orange Coordinator of this site? Confirm its status | Orange | United States | Unknown status |
| UC Irvine Health- Chao Family Comprehensive Cancer Center Coordinator of this site? Confirm its status | Orange | United States | Unknown status |
| Illinois CancerCare-Ottawa Clinic Coordinator of this site? Confirm its status | Ottawa | United States | Unknown status |
| Illinois CancerCare-Pekin Coordinator of this site? Confirm its status | Pekin | United States | Unknown status |
| Methodist Medical Center of Illinois Coordinator of this site? Confirm its status | Peoria | United States | Unknown status |
| Illinois CancerCare-Peoria Coordinator of this site? Confirm its status | Peoria | United States | Unknown status |
| Illinois CancerCare-Peru Coordinator of this site? Confirm its status | Peru | United States | Unknown status |
| Valley Radiation Oncology Coordinator of this site? Confirm its status | Peru | United States | Unknown status |
| UPMC Hillman Cancer Center Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
| UM Sylvester Comprehensive Cancer Center at Plantation Coordinator of this site? Confirm its status | Plantation | United States | Unknown status |
| Providence Portland Medical Center Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
| Providence Saint Vincent Medical Center Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
| Jefferson Healthcare Coordinator of this site? Confirm its status | Port Townsend | United States | Unknown status |
| Illinois CancerCare-Princeton Coordinator of this site? Confirm its status | Princeton | United States | Unknown status |
| Saint Luke's Hospital-Quakertown Campus Coordinator of this site? Confirm its status | Quakertown | United States | Unknown status |
| Corewell Health Reed City Hospital Coordinator of this site? Confirm its status | Reed City | United States | Unknown status |
| Marshfield Medical Center-Rice Lake Coordinator of this site? Confirm its status | Rice Lake | United States | Unknown status |
| Reid Health Coordinator of this site? Confirm its status | Richmond | United States | Unknown status |
| VCU Massey Comprehensive Cancer Center Coordinator of this site? Confirm its status | Richmond | United States | Unknown status |
| Phelps Health Delbert Day Cancer Institute Coordinator of this site? Confirm its status | Rolla | United States | Unknown status |
| Mercy Clinic-Rolla-Cancer and Hematology Coordinator of this site? Confirm its status | Rolla | United States | Unknown status |
| Sainte Genevieve County Memorial Hospital Coordinator of this site? Confirm its status | Sainte Genevieve | United States | Unknown status |
| Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Coordinator of this site? Confirm its status | Saint Joseph | United States | Unknown status |
| Corewell Health Lakeland Hospitals - Saint Joseph Hospital Coordinator of this site? Confirm its status | Saint Joseph | United States | Unknown status |
| Heartland Regional Medical Center Coordinator of this site? Confirm its status | Saint Joseph | United States | Unknown status |
| Huntsman Cancer Institute/University of Utah Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
| Guthrie Medical Group PC-Robert Packer Hospital Coordinator of this site? Confirm its status | Sayre | United States | Unknown status |
| Swedish Medical Center-First Hill Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
| Swedish Medical Center-Ballard Campus Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
| PeaceHealth United General Medical Center Coordinator of this site? Confirm its status | Sedro-Woolley | United States | Unknown status |
| Avera Cancer Institute Coordinator of this site? Confirm its status | Sioux Falls | United States | Unknown status |
| Mercy Hospital Springfield Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| CoxHealth South Hospital Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Springfield Regional Cancer Center Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Springfield Clinic Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Springfield Regional Medical Center Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Southern Illinois University School of Medicine Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Springfield Memorial Hospital Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Marshfield Medical Center-River Region at Stevens Point Coordinator of this site? Confirm its status | Stevens Point | United States | Unknown status |
| Mercy Hospital South Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| Mercy Hospital Saint Louis Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| Missouri Baptist Medical Center Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| Missouri Baptist Sullivan Hospital Coordinator of this site? Confirm its status | Sullivan | United States | Unknown status |
| Rocky Mountain Cancer Centers-Thornton Coordinator of this site? Confirm its status | Thornton | United States | Unknown status |
| Munson Medical Center Coordinator of this site? Confirm its status | Traverse City | United States | Unknown status |
| Upper Valley Medical Center Coordinator of this site? Confirm its status | Troy | United States | Unknown status |
| Dayton Physicians LLC - Troy Coordinator of this site? Confirm its status | Troy | United States | Unknown status |
| University of Arizona Cancer Center-North Campus Coordinator of this site? Confirm its status | Tucson | United States | Unknown status |
| Banner University Medical Center - Tucson Coordinator of this site? Confirm its status | Tucson | United States | Unknown status |
| Saint Luke's Cancer Institute - Twin Falls Coordinator of this site? Confirm its status | Twin Falls | United States | Unknown status |
| PeaceHealth Southwest Medical Center Coordinator of this site? Confirm its status | Vancouver | United States | Unknown status |
| Providence Saint Mary Regional Cancer Center Coordinator of this site? Confirm its status | Walla Walla | United States | Unknown status |
| Epic Care Cyberknife Center Coordinator of this site? Confirm its status | Walnut Creek | United States | Unknown status |
| Illinois CancerCare - Washington Coordinator of this site? Confirm its status | Washington | United States | Unknown status |
| Marshfield Medical Center - Weston Coordinator of this site? Confirm its status | Weston | United States | Unknown status |
| University of Michigan Health - West Coordinator of this site? Confirm its status | Wyoming | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.