NCT04708535Enrolling by invitation
Adaptive Immune Response in Visceral and Subcutaneous Fat: Role in Human Insulin Resistance
Source: ClinicalTrials.gov · Last updated 13 May 2026
Brief summary (registry, in English)
The proposed study is designed to test the hypothesis that in human obesity, the balance of pro- and anti-inflammatory T cells in fat tissue is in fact related to macrophage phenotype and insulin resistance, and how it is related. This study is needed to confirm whether conclusions based on studies of visceral adipose tissue in mice are indeed applicable to humans. We also want to determine the relationship between insulin resistance/hyperinsulinemia and ability to lose weight in obese individuals.
- Status (registry)
- Enrolling by invitation
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 3 Jul 2018
- Start date
- 1 Aug 2017
- Primary completion date
- Aug 2026
- Lead sponsor
- Stanford University
- Diseases
- Obesity
- NCT number
- NCT04708535
What you commit to
- Study type: Observational
- Planned participants: 50
- From 1 Aug 2017 to the primary completion date, Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Subjects with any clinical or biochemical evidence of significant anemia, gastrointestinal, cardiac, hepatic or renal disease will be excluded.
- Subjects with active psychiatric disorders or past history of bariatric surgery
Other
- Subjects with other medical problems may participate as long as the problems are stable.
- Pregnant or lactating women will also be excluded from the study, due to possible risk to the fetus or infant.
Who the study is looking for
- Current patients of Stanford Healthcare, Bariatric Surgery Clinic, scheduled to undergo bariatric surgery (sleeve or RYGB)
- BMI 30-55kg/m2
- 30-65 years of age
- good general health, no major organ disease
- non-diabetic by current American Diabetes Association (ADA) criteria (fasting glucose \<126mg/dl)
Age in the registry: 30 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Stanford University Coordinator of this site? Confirm its status | Stanford | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.