NCT04715984Recruiting
Corticostriatal Contributions to Parkinson's Disease Cognitive Impairment
Corticostriatal Neurophysiology in Parkinson's Disease Cognitive Impairment
Source: ClinicalTrials.gov · Last updated 12 Jun 2026
Brief summary (registry, in English)
The goal of this study is to learn more about the brain activity underlying Parkinson's disease cognitive impairment. The investigators will utilize neural recordings from corticostriatal structures performed during deep brain stimulation surgery to measure neural activity underlying nonmotor symptoms of Parkinson's disease.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 14 Jan 2021
- Start date
- 2 Jun 2021
- Primary completion date
- Aug 2029
- Lead sponsor
- Vanderbilt University Medical Center
- Diseases
- Parkinson disease
- NCT number
- NCT04715984
What you commit to
- Study type: Interventional
- Planned participants: 75
- From 2 Jun 2021 to the primary completion date, Aug 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Movement disorder other than Parkinson's disease
Age
- Age less than 40
Other
- Not able to participate in intraoperative testing (for example unable to comprehend instructions or follow directions)
Who the study is looking for
- Scheduled to undergo deep brain stimulation surgery under local anesthesia at Vanderbilt University Medical Center
- Planned clinical electrode trajectory that contacts caudate
- Age greater than or equal to 40
- Diagnosis of Parkinson's disease
- Able to participate in intraoperative testing
- English speaking
Age in the registry: 40 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vanderbilt University Medical Center Coordinator of this site? Confirm its status | Nashville | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.