NCT04726319Completed
Family History App in Personalized Medicine
Family History App in Personalized Medicine (FHAMe): A Pilot Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
A complete family history (FH) may identify persons at high risk for certain conditions. They can be offered genetic testing and life-saving screening and treatment. In practice, complete FH is rarely collected or entered into the electronic medical record (EMR). The Family History Screening Questionnaire is a survey patients complete to tell whether they are at increased risk of specific cancers, heart disease or diabetes. We will test a new way to record FH that includes an app to improve use of FH by family physicians and patients. The strategy includes education for patients and physicians about the importance of FH; patient completion of the FH questionnaire prior to appointments; and prompts in the EMR. We expect this to help family physicians and patients interpret FH and make the best decisions. We will assess the proportion of patients with new EMR FH information. We will explore if the strategy increases appropriate referrals for screening and genetic consultation for those at increased FH risk. We will also obtain patients' and physicians' feedback on this strategy. This new approach may improve FH information exchange between patients and physicians, encourage shared decision-making and reduce cancer deaths and chronic disease burden.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 627 (actual)
- First submitted
- 22 Jan 2021
- Start date
- 20 Sept 2021
- Primary completion date
- 30 Jun 2022
- Lead sponsor
- University of Toronto
- Diseases
- Prostate cancer, Coronary artery disease, Melanoma, Colorectal cancer, Ovarian cancer, Type 2 diabetes
- NCT number
- NCT04726319
What you commit to
- Study type: Interventional
- Participants enrolled: 627
- From 20 Sept 2021 to the primary completion date, 30 Jun 2022
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Pregnancy
- Must be patients of staff physicians (i.e. no resident patients)
- Must have email address registered in the OCEAN system
Who the study is looking for
- 30-69 years of age
Age in the registry: 30 years to 69 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mount Sinai Hospital Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.