NCT04741711Recruiting
AMBulatory UltraSound for Heart Failure Management
Impact of Ultrasound-guided Therapeutic Management of Ambulatory Patients With Heart Failure : An Open-label Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 17 May 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
AMBUSH study is a multicenter randomized, controlled, open-label clinical trial (PROBE (Prospective Randomized Open Blinded End-point) type). The main objective of AMBUSH study is to assess the effect of therapeutic management guided by pulmonary ultrasound and the assessment of the inferior vena cava in patients with heart failure seen in an ambulatory (outpatient) setting on a mixed clinical-biological endpoint (including variations of natriuretic peptides - NtProBNP) at 30 days.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 182 (estimated)
- First submitted
- 29 Jan 2021
- Start date
- 15 May 2023
- Primary completion date
- 15 Jun 2026
- Lead sponsor
- Central Hospital, Nancy, France
- Diseases
- Heart failure
- NCT number
- NCT04741711
What you commit to
- Study type: Interventional
- Planned participants: 182
- From 15 May 2023 to the primary completion date, 15 Jun 2026
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Natriuretic peptides result, carried out during the previous 30 days, available at the inclusion consultation
Other illness
- Suspicion of cardiac amyloidosis or proven amyloidosis,
- Patient with severe primary heart valve disease
- Person subject to psychiatric care pursuant to Articles L. 3212-1 and L. 3213-1 of the Public Health Code.
Other
- Pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images: severe emphysema, chronic pleurisy, pulmonary fibrosis.
- Pregnant woman, parturient or nursing mother
- Adult person subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
- Person deprived of liberty by a judicial or administrative decision,
Who the study is looking for
- Male or female aged 18 and over
- Heart failure (regardless of left ventricular ejection fraction)
- Diagnosis of heart failure established more than 3 months ago
- Absence of significant clinical signs of congestion on clinical examination (absence of crackles and lower limbs oedema greater than perimalleolar oedema)
- Affiliation to social security
- Receiving complete information about research organization and signed informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Besançon Coordinator of this site? Confirm its status | Besançon | France | Not yet recruiting |
| CH de Mulhouse Coordinator of this site? Confirm its status | Mulhouse | France | Not yet recruiting |
| CHRU de Reims Coordinator of this site? Confirm its status | Reims | France | Not yet recruiting |
| CHR de Metz Coordinator of this site? Confirm its status | Thionville | France | Not yet recruiting |
| CHRU de Nancy Coordinator of this site? Confirm its status | Vandœuvre-lès-Nancy | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.