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NCT04743466Active, not recruiting

Evaluation of Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes

Evaluation of a Causal Association Between Testosterone Levels, Dementia, and Adverse Mental Health Outcomes: A Mendelian Randomization Analysis

Source: ClinicalTrials.gov · Last updated 19 Feb 2026

Brief summary (registry, in English)

This study evaluates the association between testosterone levels and risk of dementia and adverse mental health outcomes (e.g. depression and anxiety). It is not known whether low testosterone levels may be associated with an increased risk of dementia. Learning about the association between testosterone levels and risk of dementia may help determine the long-term effects of androgen deprivation therapy and may help improve quality of life.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
1 (actual)
First submitted
3 Feb 2021
Start date
13 Feb 2020
Primary completion date
30 Nov 2028
Lead sponsor
M.D. Anderson Cancer Center
NCT number
NCT04743466

What you commit to

  • Study type: Observational
  • Participants enrolled: 1
  • From 13 Feb 2020 to the primary completion date, 30 Nov 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

  • Have volunteered to participate in institutional or national biobanks, mainly the UK Biobank and the Kaiser Permanente Research Bank, and those that have previously participated in studies that resulted in de-identified clinical and genetic data being make available on public archives, mainly the database of Genotypes and Phenotypes (dbGaP)
  • No special populations (adults unable to consent, individuals not yet adults, pregnant women, or prisoners)

Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
M D Anderson Cancer Center
Coordinator of this site? Confirm its status
HoustonUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.