NCT04743674Recruiting
Blood and Urine HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Treatment
Plasma Circulating Tumor HPVDNA and Transrenal HPVDNA as Minimally Invasive Biomarkers for Cervical Cancer Detection and Surveillance Following Definitive Treatment
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
The purpose of this study is to determine if ctHPVDNA (circulating tumor HPV DNA) can be used as a non-invasive biomarker for identification and treatment monitoring of cervical cancer by characterizing correlation between plasma ctHPVDNA, urine transrenal HPVDNA (TrHPVDNA) levels and presence of cervical cancer at diagnosis and following definitive intent management.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 30 (estimated)
- First submitted
- 3 Feb 2021
- Start date
- 3 May 2024
- Primary completion date
- 15 Jan 2027
- Lead sponsor
- UNC Lineberger Comprehensive Cancer Center
- Diseases
- Cervical cancer
- NCT number
- NCT04743674
What you commit to
- Study type: Observational
- Planned participants: 30
- From 3 May 2024 to the primary completion date, 15 Jan 2027
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Women who are pregnant
Who the study is looking for
- 18 years of age or older on day of signing informed consent
- New diagnosis of cervical cancer
- Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kamuzu Central Hospital Coordinator of this site? Confirm its status | Lilongwe | Malawi | Not yet recruiting |
| Melissa Knutsen Coordinator of this site? Confirm its status | Chapel Hill | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.