NCT04746729Recruiting
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy (HARMONIC-RT)
Source: ClinicalTrials.gov · Last updated 3 Aug 2026
Brief summary (registry, in English)
The goal of the HARMONIC-RT study is to evaluate late health and social outcomes of contemporary techniques of external beam radiotherapy in paediatric patients, based on the setting-up of a European, long-term registry complemented by a biobank.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 2670 (estimated)
- First submitted
- 14 Sept 2020
- Start date
- 11 Jan 2021
- Primary completion date
- 30 Jan 2032
- Lead sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
- Diseases
- Childhood cancers
- NCT number
- NCT04746729
What you commit to
- Study type: Observational
- Planned participants: 2670
- From 11 Jan 2021 to the primary completion date, 30 Jan 2032
- 5 sites in 4 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior external or internal radiation therapy
- Prior external or internal radiation therapy;
Other
- Patients with poor prognosis (e.g. diffuse pontine glioma or high grade glioma) at first EBRT initiation
- Patients who refused to participate in the study
- Prospective inclusion of study participants
- Patients with poor prognosis (e.g. diffuse pontine glioma or high grade glioma)
- Protected adults (persons under curatorship, tutorship / individuals under guardianship by court order, persons deprived of their liberty)
- Adult/parent(s)/legal representative(s) who cannot read or understand the informed consent in the applicable language(s) in the country of EBRT
Who the study is looking for
- First external beam radiation therapy (EBRT) started in 2000 or after for management of a first primary neoplasm
- Age under 22 years at the time of first EBRT initiation
- Radiation treatment plan (first EBRT) stored in DICOM format
- Usual residency in the country of EBRT to enable a long-term follow-up
- Scheduled first EBRT for management of a first primary neoplasm
- Age under 22 years at the time of scheduled first EBRT
- Radiation treatment plan stored in DICOM format
- Affiliate or beneficiary of health insurance (or any required equivalent as defined in applicable national law)
- Usual residency in the country of EBRT to enable a long-term follow-up
- Signed informed consent/assent
Criteria the registry did not label
- Retrospective inclusion of study participants
Age in the registry: - to 22 years · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| KU Leuven Coordinator of this site? Confirm its status | Leuven | Belgium | Recruiting |
| University Hospital Essen, The West German Proton Therapy Centre Essen Coordinator of this site? Confirm its status | Essen | Germany | Recruiting |
| Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Recruiting |
| Centre Regional Francois Baclesse Coordinator of this site? Confirm its status | Caen | France | Recruiting |
| Gustave Roussy Coordinator of this site? Confirm its status | Villejuif | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.