NCT04751292Completed
HIGH Altitude CArdiovascular REsearch Latin America Population Study
Source: ClinicalTrials.gov · Last updated 1 Mar 2024
Brief summary (registry, in English)
High blood pressure (BP) is one of the principal cardiovascular risk factors. While BP levels and hypertension prevalence are well characterized in many populations, information on BP and on cardiovascular risk profile in high altitude inhabitants is limited and frequently contradictory, especially in the large highland populations of South America. The information on the effects of permanent high altitude exposure on cardiovascular variables including BP may be relevant in the light of the known BP-increasing effect of acute exposure to high altitude hypoxia. This information may have practical implications for millions of people living at elevated altitudes in Asia, South America and Africa. The inconclusive epidemiological evidence on BP and cardiovascular risk in high altitude dwellers may be the result of several factors, among them: 1) confounding by genetic and socio-economic factors; 2) imperfect methods of BP evaluation, in particular lack of data on ambulatory and home BP (both methods considered superior to conventional clinic BP in the assessment of exposure to high BP). On this background, the general aim of the study is to compare blood pressure levels and cardiovascular risk profile among population-based samples of subjects residing in Peruvian communities living at different altitudes.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 937 (actual)
- First submitted
- 2 Feb 2021
- Start date
- 26 Jan 2021
- Primary completion date
- 30 Dec 2023
- Lead sponsor
- Istituto Auxologico Italiano
- Diseases
- High blood pressure
- NCT number
- NCT04751292
What you commit to
- Study type: Observational
- Participants enrolled: 937
- From 26 Jan 2021 to the primary completion date, 30 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Active pulmonary tuberculosis
Other
- Lowlanders who over 3 months preceding inclusion in the study spent considerable (\> 7 consecutive days) amount of time at altitudes above 1500 m;
- Highlanders who over 3 months preceding inclusion in the study spent considerable (\>7 consecutive days) amount of time at altitudes below 2500 m;
- Subjects cognitively incapable of providing informed consent or responding to a questionnaire
- Physical disability that would prevent study assessments from being performed
- Pregnancy
Who the study is looking for
- Adult (\>18 years) male and female subjects;
- Highlanders: permanence at high (\>2500 m) altitude;
- Lowlanders: permanence at low (\<1500 m) altitude;
- Written informed consent to participate in the study
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad Peruana Cayetano Heredia Coordinator of this site? Confirm its status | Lima | Peru | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.