NCT04755439Completed
Evaluation of Cerebral Parenchymal Changes in Patients Undergoing Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest Using Diffusion MRI
Evaluation of Cerebral Parenchymal Changes in Patients Undergoing Proximal Aortic Surgery With Deep Hypothermic Circulatory Arrest Using Diffusion MR
Source: ClinicalTrials.gov · Last updated 30 May 2025
Brief summary (registry, in English)
Deep hypothermic circulatory arrest (DHCA) (18 degree) without cerebral perfusion is a safe technique. Resarchers use this technique in patients with proximal aortic pathologies. During the DHCA period, cerebral silent ischemic events may occur. But the silent ischemic events don't neurological problems with patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 35 (actual)
- First submitted
- 28 Jan 2021
- Start date
- 10 Dec 2020
- Primary completion date
- 1 Jan 2024
- Lead sponsor
- Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
- NCT number
- NCT04755439
What you commit to
- Study type: Interventional
- Participants enrolled: 35
- From 10 Dec 2020 to the primary completion date, 1 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- outside the age range of 18-85, emergency surgery,
Other
- Patients without ascending aortic and aortic root aneurysms
- Exceeding the magnetic resonance imaging extraction time limit.
Who the study is looking for
- Patients with ascending aorta and aortic root aneurysm.
- 18-85 years old
Age in the registry: 18 years to 85 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Dr. Siyami Ersek Thoracic And Cardiovascular Surgery Training And Research Hospital. Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
Related publications
- Silent cerebral infarction after proximal thoracic aortic surgery under deep hypothermic circulatory arrest: an exploratory prospective DW-MRI study.BMC Cardiovasc Disord · 2026 · PMID 42402559
This page is information, not medical advice. Discuss any trial with your doctor.