NCT04759898Completed
Direct Measurement of Motor Cortical Responses to tDCS
Direct Measurement of Motor Cortical Responses to Transcranial Direct Current Stimulation
Source: ClinicalTrials.gov · Last updated 1 May 2026
Brief summary (registry, in English)
Transcranial direct current stimulation (tDCS) has shown the potential to improve symptoms in patients with movement deficits, such as Parkinson's disease and chronic stroke. However, the effects of tDCS have so far not been proven on a wider scale due to lack of knowledge regarding exactly how tDCS works. This has limited the adoption of this potentially useful therapy for patients with Parkinson's disease, chronic stroke and other conditions affecting movement. The investigators hypothesize that by studying the effects of tDCS in subjects performing a motor task, the brain signals mediating improvements in motor control will be identified. The investigators will use both noninvasive and invasive methods to explore this hypothesis. The investigators expect this combined approach to broaden understanding of tDCS application in conditions affecting movement and possibly lead to therapeutic advances in these populations.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 20 (actual)
- First submitted
- 21 Dec 2020
- Start date
- 1 Jan 2021
- Primary completion date
- 1 Jan 2025
- Lead sponsor
- Medical University of South Carolina
- Diseases
- Parkinson disease
- NCT number
- NCT04759898
What you commit to
- Study type: Observational
- Participants enrolled: 20
- From 1 Jan 2021 to the primary completion date, 1 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior history of seizures
- Metal implants in head or neck
- Prior intracranial surgery
- Prior brain radiotherapy
- Prior history of intracranial tumor, intracranial infection or cerebrovascular malformation
Other illness
- Presence of scalp injury or disease
Other
- Subjects unable to actively participate in the consent process physically and/or cognitively
- Pregnancy
Who the study is looking for
- Age 18 or older
- Previous consent to be contacted regarding potential participation in a research study at Medical University of South Carolina
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Medical University of South Carolina Coordinator of this site? Confirm its status | Charleston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.