NCT04766710Completed
Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia
Implementation and Evaluation of a Community-Based Model for Delivery of Antiretroviral Therapy in Cambodia: A Quasi-Experimental Study
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
The community-based ART delivery (CAD) model will build on the existing framework to engage community action, operationalized in the current Global Fund-supported project. Community Action Workers (CAW), who are assigned to ART centers and conduct outreach work, are well-suited to administer CAD scheme. KHANA and the project partners all have implementation roles in the Global Fund-supported project and established working channels with the CAW. While the previous experiences suggest the CAD model's effectiveness, implementing it in Cambodia requires adaptation to its specific local context. The proposed project will be implemented as an implementation study in nine ART sites and supported by a concrete evaluation plan. KHANA Center for Population Health Research will lead the research component. The project has three strategic areas and corresponding deliverables as follows: A. The development of a locally-fitted model: bringing ART closer to the people living with HIV B. The research: formulation, evaluation, documentation, and dissemination of the evidence, knowledge, and lessons learned C. The scale-up: advocacy for the SOP development to replicate/scale-up the CAD model The project will benefit a wide range of stakeholders. The approximately 2,000 ART clients enrolled in the nine selected clinics will face less cost, time, and discrimination, which will also benefit their families. The clinics will have a reduced workload on site, and they would be able to improve the quality of care for the visiting clients. The Cambodian health system will obtain a CAD model tailored to the country's local context and develop Standard Operating Procedures for the scheme with readily involved stakeholders. The scale-up of the model will benefit all other ART clinics and clients in the country. The 36-months project starting from June 1, 2019, will include six months of start-up and baseline assessments, 24-month intervention, and six-month evaluation.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 4049 (actual)
- First submitted
- 15 Jan 2021
- Start date
- 1 Apr 2021
- Primary completion date
- 31 Mar 2023
- Lead sponsor
- National University of Singapore
- Diseases
- HIV
- NCT number
- NCT04766710
What you commit to
- Study type: Interventional
- Participants enrolled: 4049
- From 1 Apr 2021 to the primary completion date, 31 Mar 2023
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Unstable people living with HIV as defined above
Other
- Mobile populations
Who the study is looking for
- Receiving ART for at least one year.
- No adverse drug reactions or ARV drug interactions requiring regular monitoring.
- No suspected or confirmed tuberculosis, no other opportunistic infections, and not on any prophylaxis.
- Not pregnant/breastfeeding (for women).
- Having a good understanding of lifelong treatment and adherence to the medication.
- Presenting with evidence of treatment success: two consecutive undetectable viral load measures (or, in the absence of viral load monitoring, CD4 counts above 200 cells/mm3 and objective adherence measure).
- Aged ≥15 years.
- On the first-line ARV regimen.
Age in the registry: 15 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cambodia Anti-Tuberculosis Association Coordinator of this site? Confirm its status | Phnom Penh | Cambodia | Unknown status |
| KHANA Center for Population Health Research Coordinator of this site? Confirm its status | Phnom Penh | Cambodia | Unknown status |
| National Center for Tuberculosis and Leprosy Control Coordinator of this site? Confirm its status | Phnom Penh | Cambodia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.