NCT04767568Recruiting
Exploratory Study of the Relevance of a Blood Test in the Management of Patients in the Context of Colorectal Cancer Screening
Source: ClinicalTrials.gov · Last updated 16 Mar 2026
Brief summary (registry, in English)
Colorectal cancer (CRC) is the third most common cancer in men and the second in women with an incidence of 43,350 new cases in 2018. This incidence is increasing every year. Early detection is crucial in this pathology. In France, free screening is organized by health insurance for people aged 50 to 74 years. This screening is based on an immunological test (FIT: Fecal Immunological test), which aims to detect the presence of blood in the stool. In fact, some polyps or cancers cause bleeding that is often minimal and therefore difficult or even impossible to detect with the naked eye. If this test is positive, a colonoscopy is done to check whether or not abnormalities are present in the colon or rectum. Performed under anesthesia, this examination can detect the possible presence of polyps or cancer. Recently, with the covid-19 epidemic, the investigators were faced with an extension of the delays for colonoscopies which led to delays in patient care. To prevent this, they propose to develop a blood test that would allow rapid identification of patients with colorectal cancer, requiring rapid management. This blood test will permit to have a parameter for stratifying the therapeutic care in the event of epidemia or situation that constrains the organisation of the health system.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 400 (estimated)
- First submitted
- 3 Dec 2020
- Start date
- 30 Mar 2021
- Primary completion date
- Aug 2027
- Lead sponsor
- Centre Hospitalier Universitaire de Besancon
- Diseases
- Colorectal cancer
- NCT number
- NCT04767568
What you commit to
- Study type: Interventional
- Planned participants: 400
- From 30 Mar 2021 to the primary completion date, Aug 2027
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Vulnerable persons according to the law (minors, adults under protection, persons deprived of liberty ...)
- Not ability to comply with the study protocol, in the Investigator's judgment
- pregnant woman
- Patient in the period of exclusion of another study
Who the study is looking for
- Patients aged more than18 years
- Cohort A : patients with suspected colorectal cancer following a positive immunological test during screening (presence of blood detected in the stool) or with gross bleeding OR Cohort B : patients who have already performed colonoscopy (on symptoms, or because of family history, or other ...), for whom the diagnosis of adenocarcinoma was identified by pathology prior to surgery, candidates for surgery on their colorectal tumor
- Signed and dated informed consent
- Patient affiliated to or beneficiary of French social security system.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CHU de Besançon Coordinator of this site? Confirm its status | Besançon | France | Recruiting |
| Hôpital Nord Franche-Comté Coordinator of this site? Confirm its status | Montbéliard | France | Not yet recruiting |
| Centre Hospitalier Intercommunal de Haute-Saône Coordinator of this site? Confirm its status | Vesoul | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.