NCT04770090Active, not recruiting
Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Preliminary Descriptive Exploratory Pilot Study Research of Circulating Tumor Cells Released During Cervical Cancer Surgery
Source: ClinicalTrials.gov · Last updated 22 Jun 2026
Brief summary (registry, in English)
Cervical cancer is a rare pathology. Recent studies showed that the risk of recurrence is higher for patients treated by coelioscopy in comparison with laparotomy. It could be explained by the spread of circulating tumor cells (CTC) due to tumor mobilization during different steps of the surgery. The primary goal is to evaluate the spread of CTC during surgery on peripheral blood samples. The secondary outcome is to evaluation the disease-free survival at 3 and 5 years postoperatively. 20 patients with early stage cervical (IA1 to IB2) eligible to coelioscopic stadification and laparoscopic surgery will be included.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 4 Feb 2021
- Start date
- 10 Mar 2022
- Primary completion date
- 5 Dec 2022
- Lead sponsor
- University Hospital, Montpellier
- Diseases
- Cervical cancer
- NCT number
- NCT04770090
What you commit to
- Study type: Interventional
- Participants enrolled: 200
- From 10 Mar 2022 to the primary completion date, 5 Dec 2022
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant cancer
Other illness
- Participation to other study that may have an impact on the prognosis of cervical cancer
Other
- Advanced stage (Stage IB3 and more)
- Pregnant or breastfeeding woman
- Vulnerable person (Article L1121-6 of the Public Health Code)
- Participation to other study with an exclusion period still in progress
Who the study is looking for
- Woman \>18 years old
- Cervical cancer confirmed by histology
- Early stage eligible for immediate surgical treatment (or post-brachytherapy): stages IA1, 1A2, 1B1 and IB2 with or without emboli determined by MRI performed as part of the treatment
- Histology : epidermoid carcinoma and adenocarcinoma
- Valid Social Security
- Wrote consent
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut du Cancer de Montpellier - Val d'Aurelle Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| Department of gynaecology, Montpellier University Hospital Coordinator of this site? Confirm its status | Montpellier | France | Unknown status |
| CHU de Nîmes Coordinator of this site? Confirm its status | Nîmes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.