NCT04782466Active, not recruiting
ATOMIC (Active Teens Multiple Sclerosis) Physical Activity Research Program
Physical Activity, Quality of Life and Disease Outcomes in Youth With Multiple Sclerosis: the ATOMIC (Active Teens Multiple Sclerosis) Physical Activity Research Program
Source: ClinicalTrials.gov · Last updated 23 Sept 2025
Brief summary (registry, in English)
The investigators have previously shown that youth with MS are very inactive, and that vigorous physical activity is associated with higher levels of well-being and lower MS disease activity in youth. Yet, no effective physical activity interventions have been developed for youth with MS to date. The investigators have taken input from youth with MS to create a Smartphone-based app (the ATOMIC - Active Teens with Multiple Sclerosis - App) that provides tailored physical activity information and coaching, provides tools to increase social connectedness, and promotes physical activity. This proposed research will therefore address the problem of inactivity in youth with MS by studying an intervention to increase physical activity.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 56 (estimated)
- First submitted
- 23 Feb 2021
- Start date
- 1 Dec 2020
- Primary completion date
- Sept 2025
- Lead sponsor
- The Hospital for Sick Children
- Diseases
- Multiple sclerosis
- NCT number
- NCT04782466
What you commit to
- Study type: Interventional
- Planned participants: 56
- From 1 Dec 2020 to the primary completion date, Sept 2025
- 3 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Are at increased risk of cardiac or other complications of exercise testing (e.g. cardiac disease, diabetes), as determined by the pediatric neurologist or physician.
Other
- Have non-specific white matter abnormalities and metabolic or infectious etiologies for white matter abnormalities;
- Do not speak and read English at a level needed to complete the questionnaires (4th grade level);
- Have significant motor disability, classified as an Expanded Disability Status Scale (EDSS) ≥4;
Who the study is looking for
- Youth 11-21 years of age;
- MS diagnosis or clinically isolated syndrome, as per revised McDonald diagnostic criteria and International Pediatric MS Study Group criteria prior to the age of 18;
- Participating in less than three hours of structured physical activity per week.
Age in the registry: 11 years to 21 years · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Hospital for Sick Children Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
| The University of Alabama at Birmingham Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| Children's Hospital of Philadelphia Coordinator of this site? Confirm its status | Philadelphia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.