NCT04788628Enrolling by invitation
Auditory Stimulation Effects on Sleep and Memory in Patients With Epilepsy
Effects of Auditory Stimulation on Coordinated Non-REM Sleep Oscillations and Memory in Epilepsy Inpatients With Implanted Hippocampal Electrodes
Source: ClinicalTrials.gov · Last updated 17 Nov 2025
Brief summary (registry, in English)
This study will investigate the role of coordinated brain rhythms during sleep in memory consolidation and determine whether playing precisely timed brief bursts of noise can enhance these rhythms and improve memory in epilepsy inpatients with implanted hippocampal electrodes.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 25 Feb 2021
- Start date
- Jan 2021
- Primary completion date
- Mar 2026
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Epilepsy
- NCT number
- NCT04788628
What you commit to
- Study type: Interventional
- Planned participants: 24
- From Jan 2021 to the primary completion date, Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous surgery anticipated to disrupt coordination of sleep oscillations in the circuitry of interest
Other
- Intellectual disability impairing ability to perform task
- Motor problems that preclude finger tapping task
Who the study is looking for
- Inpatients with epilepsy
- Aged 12-65
- Undergoing clinically indicated continuous scalp and intracranial EEG monitoring with implanted hippocampal electrodes
- Fluent in English
- Able to give informed consent/assent (for minors aged 12-17 or adults with an appointed guardian)
Age in the registry: 12 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.