NCT04793867Recruiting
Regional Phenotyping of CF and Non-CF Bronchiectasis
Regional Phenotyping of Cystic Fibrosis Lung Disease and Non-CF Bronchiectasis
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
The Investigators propose to study pediatric subjects who are diagnosed with cystic fibrosis (CF) and patients with non-CF bronchiectasis, with the goal of developing markers of CF lung disease severity, progression, and therapy response. The Investigator's central hypothesis is that image-based markers can forecast pathophysiology prior to spirometric changes.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 100 (estimated)
- First submitted
- 23 Feb 2021
- Start date
- 8 Feb 2021
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Children's Hospital Medical Center, Cincinnati
- Diseases
- Cystic fibrosis
- NCT number
- NCT04793867
What you commit to
- Study type: Observational
- Planned participants: 100
- From 8 Feb 2021 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients meeting standard MRI exclusions criteria (non-MRI-compatible metal implants, claustrophobia, etc.)
- Patients meeting standard MRI exclusions criteria (non-MRI-compatible metal implants, claustrophobia, etc.)
Other
- Pregnancy or lactation.
- Pregnancy or lactation.
Who the study is looking for
- CF Patients: Diagnosis of CF based on sweat chloride \>60 mMol/l
- Presence of two disease causing CFTR mutations, or end organ manifestations of disease.
- Age minimum 5 years.
- Care provided by the CCHMC CF Care Center or other regional CF Care Centers if required to achieve recruitment goals.
- Subjects 5 years of age and older with no known history of cardiopulmonary disease.
Age in the registry: 5 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penny New Coordinator of this site? Confirm its status | Cincinnati | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.