NCT04797403Active, not recruiting
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline
Effectiveness of Implementing an Intensive Blood Pressure Reduction Intervention on Cognitive Decline in Low-Income and Minority Hypertensive Patients
Source: ClinicalTrials.gov · Last updated 1 Oct 2026
Brief summary (registry, in English)
The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP \<120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in primary care. The proposed study will generate urgently needed data on effective, adoptable, and equitable intervention strategies to reduce blood pressure-related cognitive decline in low- income and minority populations. If proven effective, the implementation strategy for intensive blood pressure reduction could be adapted and scaled up in diverse primary care settings to prevent cognitive decline and clinical dementia.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 1306 (actual)
- First submitted
- 8 Mar 2021
- Start date
- 22 Oct 2019
- Primary completion date
- 31 Oct 2026
- Lead sponsor
- Tulane University
- Diseases
- High blood pressure
- NCT number
- NCT04797403
What you commit to
- Study type: Interventional
- Participants enrolled: 1306
- From 22 Oct 2019 to the primary completion date, 31 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Predominantly managing underserved populations with health disparities (ethnic minorities, low-income groups, and residents of rural areas and inner cities).
- Having electronic medical record systems.
- Serving \>200 hypertension patients (ICD-10-CM I10-I15) during the previous year.
- Not participating in other hypertension control programs
- Not sharing providers or nurses/pharmacists with other participating clinics.
- Men or women aged ≥40 years (2/3 of participants ≥60 years) who receive primary care from participating clinics.
- Systolic BP ≥ 140 mmHg at two screening visits for those not taking antihypertensive medication or systolic BP ≥ 130 mmHg at two screening visits for those taking antihypertensive medications
- Pregnant women, women planning to become pregnant in the near future, women of childbearing potential and not practicing birth control, and persons who cannot give informed consent will be excluded.
- No diagnosis of dementia at baseline
- Baseline MoCA score ≥ 10.
- No diagnosis of end-stage renal disease, defined as dialysis or transplantation
- Speak English as first language
- No plans to change to a primary healthcare provider outside of their clinic in the near future
- No individuals unlikely to complete the study, such as those who plan to move out of the study area in the near future and temporary migrant and homeless people
- No immediate family members are staff at their clinic
Age in the registry: 40 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tulane University Coordinator of this site? Confirm its status | New Orleans | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.