NCT04812314Recruiting
Exercise Effects on Adipose Tissue Structure and Function
Source: ClinicalTrials.gov · Last updated 4 Jun 2026
Brief summary (registry, in English)
Participants will be randomized into one of two different experimental groups: 1) Exercise group and 2) No exercise (control group). Subject participation in the study will involve a series of metabolic tests before and after participants undergo a 10% weight loss program (with or without exercise training depending on group randomization). After completing this weight loss portion of the study, participants will then be required to adhere to a high calorie diet program to regain half of the weight the participant lost - followed by the same series of metabolic tests.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 46 (estimated)
- First submitted
- 19 Mar 2021
- Start date
- 1 Mar 2021
- Primary completion date
- 1 Mar 2028
- Lead sponsor
- University of Michigan
- Diseases
- Obesity
- NCT number
- NCT04812314
What you commit to
- Study type: Interventional
- Planned participants: 46
- From 1 Mar 2021 to the primary completion date, 1 Mar 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Evidence/history of cardiovascular or metabolic disease
Lab values
- Medications known to affect lipid or glucose metabolism, or inflammation
Other
- Weight instability ≥ ± 6 pounds in the last 3 months
- Tobacco or e-cigarette users
- Women must not be pregnant or actively lactating
Who the study is looking for
- Age: 18-40
- Body Mass Index: 27-45 kg/m2
- No regularly planned exercise/physical activity for at least 6 months
- Women must have regularly occurring menses and must be premenopausal
Age in the registry: 18 years to 40 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Michigan Coordinator of this site? Confirm its status | Ann Arbor | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.