NCT04817449Completed
Spectroscopy in Ovarian Cancer
Molecular Spectroscopy in Identification and Assessment of Ovarian Cancer
Source: ClinicalTrials.gov · Last updated 19 Dec 2025
Brief summary (registry, in English)
Ovarian cancer is the eighth most common cause of cancer death in the world. Advanced stage at diagnosis is associated with lower survival rates, thus early detection appears to have an important role. Raman Spectroscopy is a non-invasive technique that uses the interaction of light to identify the composition of the sample tested. The aim of the project is to explore the use of spectroscopic techniques in the detection of ovarian cancer. There are two different assessments within the project: 1. Identify ovarian cancer in blood - Raman spectroscopic analysis will be performed on blood plasma taken from patients with suspected ovarian cancer. 2. Detect active cancer within post chemotherapy fibrotic tissue - Ex vivo Raman spectroscopic analysis of peritoneal, omental or ovarian tissues collected from patients undergoing surgical treatment for ovarian cancer. The results of the spectroscopy will be correlated to clinical outcome and histological diagnosis respectively.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 160 (actual)
- First submitted
- 4 Mar 2021
- Start date
- 28 Jun 2021
- Primary completion date
- 1 Oct 2023
- Lead sponsor
- University of Exeter
- Diseases
- Ovarian cancer
- NCT number
- NCT04817449
What you commit to
- Study type: Observational
- Participants enrolled: 160
- From 28 Jun 2021 to the primary completion date, 1 Oct 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Less than 18 years of age
Other
- Unable to consent to the study due to communication difficulties
- Unable to consent to the study due to lack of capacity
Who the study is looking for
- Female
- Symptoms suggestive of ovarian cancer
- Patients undergoing treatment of Ovarian Cancer
Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Hospitals Bristol and Weston NHS Trust Coordinator of this site? Confirm its status | Bristol | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.