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NCT04817449Completed

Spectroscopy in Ovarian Cancer

Molecular Spectroscopy in Identification and Assessment of Ovarian Cancer

Source: ClinicalTrials.gov · Last updated 19 Dec 2025

Brief summary (registry, in English)

Ovarian cancer is the eighth most common cause of cancer death in the world. Advanced stage at diagnosis is associated with lower survival rates, thus early detection appears to have an important role. Raman Spectroscopy is a non-invasive technique that uses the interaction of light to identify the composition of the sample tested. The aim of the project is to explore the use of spectroscopic techniques in the detection of ovarian cancer. There are two different assessments within the project: 1. Identify ovarian cancer in blood - Raman spectroscopic analysis will be performed on blood plasma taken from patients with suspected ovarian cancer. 2. Detect active cancer within post chemotherapy fibrotic tissue - Ex vivo Raman spectroscopic analysis of peritoneal, omental or ovarian tissues collected from patients undergoing surgical treatment for ovarian cancer. The results of the spectroscopy will be correlated to clinical outcome and histological diagnosis respectively.

Status (registry)
Completed
Study type
Observational
Enrollment
160 (actual)
First submitted
4 Mar 2021
Start date
28 Jun 2021
Primary completion date
1 Oct 2023
Lead sponsor
University of Exeter
NCT number
NCT04817449

What you commit to

  • Study type: Observational
  • Participants enrolled: 160
  • From 28 Jun 2021 to the primary completion date, 1 Oct 2023
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Less than 18 years of age

Other

  • Unable to consent to the study due to communication difficulties
  • Unable to consent to the study due to lack of capacity

Who the study is looking for

  • Female
  • Symptoms suggestive of ovarian cancer
  • Patients undergoing treatment of Ovarian Cancer

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University Hospitals Bristol and Weston NHS Trust
Coordinator of this site? Confirm its status
BristolUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.