NCT04823377Active, not recruiting
Impact of a Process Optimizing the Decision to Continue or Stop Cancer Treatments in Patients With Advanced Non-small Cell Lung Cancer.
Source: ClinicalTrials.gov · Last updated 28 Nov 2025
Brief summary (registry, in English)
Sequential comparative prospective interventional study evaluating the impact of the use of an optimization device of the decision of cancer treatment on aggressiveness of end of life care. Comparison between a first period, period (A), of care as usual and a second period, period (B), of systematic and iterative use of a device for optimizing the decision to continue an anti-cancer treatment.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 364 (estimated)
- First submitted
- 29 Mar 2021
- Start date
- Sept 2021
- Primary completion date
- Sept 2026
- Lead sponsor
- Institut Curie
- Diseases
- Lung cancer
- NCT number
- NCT04823377
What you commit to
- Study type: Interventional
- Planned participants: 364
- From Sept 2021 to the primary completion date, Sept 2026
- 25 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Small Cell Lung Cancer (including mixed forms).
- Patient with NSCLC for whom a decision has already been made to permanently discontinue all systemic cancer treatment.
Other
- Impossible follow up for geographical, social or psychological reason.
- Inability to answer a questionnaire (language or neurological barrier).
- Patient under guardianship.
- Patient being treated in a therapeutic trial.
- Patient not covered by social security. -
Who the study is looking for
- Histologically or cytologically proven non-small-cell lung carcinoma (NSCLC) including NSCLC with oncogene addiction.
- Stage IV or IIB/IIIC non irradiable (8th classification TNM, UICC 2015)
- Patient having completed at least one line of chemotherapy in the context of metastatic disease (or in the context of locoregional disease if the last chemotherapy was less than 6 months ago).
- ECOG Performance Status ≥ 2.
- Age ≥ 18.
- Written informed consent.
- Patient capable, according to the investigator, to comply with the requirements of the study.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (25)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| CH Abbeville Coordinator of this site? Confirm its status | Abbeville | France | Unknown status |
| CH du Pays d Aix Coordinator of this site? Confirm its status | Aix-en-Provence | France | Unknown status |
| CHU AMIENS - Hôpital Sud Coordinator of this site? Confirm its status | Amiens | France | Unknown status |
| CHU Angers Coordinator of this site? Confirm its status | Angers | France | Unknown status |
| CHR Metz-Thionville - Hôpital de Mercy Coordinator of this site? Confirm its status | Ars-Laquenexy | France | Unknown status |
| CH Henri Duffaut Avignon Coordinator of this site? Confirm its status | Avignon | France | Unknown status |
| Institut Sainte-Catherine Coordinator of this site? Confirm its status | Avignon | France | Unknown status |
| AP-HP Ambroise Paré Coordinator of this site? Confirm its status | Boulogne-Billancourt | France | Unknown status |
| CHI de Compiègne-Noyon Coordinator of this site? Confirm its status | Compiègne | France | Unknown status |
| CHU Sud Francilien Coordinator of this site? Confirm its status | Corbeil-Essonnes | France | Unknown status |
| Clinique des Cèdres Coordinator of this site? Confirm its status | Cornebarrieu | France | Unknown status |
| CH Intercommunal de Créteil Coordinator of this site? Confirm its status | Créteil | France | Unknown status |
| CGFL Coordinator of this site? Confirm its status | Dijon | France | Unknown status |
| CHU Grenoble Alpes Coordinator of this site? Confirm its status | Grenoble | France | Unknown status |
| CHD Vendée Coordinator of this site? Confirm its status | La Roche-sur-Yon | France | Unknown status |
| CHRU Lille Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Centre Leon Berard Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| AP-HP Bichat Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Institut Curie Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| AP-HP Tenon Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| AP-HP Cochin Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| Institut Curie Coordinator of this site? Confirm its status | Saint-Cloud | France | Unknown status |
| CH Saint-Malo Coordinator of this site? Confirm its status | St-Malo | France | Unknown status |
| Hopital Foch Coordinator of this site? Confirm its status | Suresnes | France | Unknown status |
| Clinique Tessier Coordinator of this site? Confirm its status | Valenciennes | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.