NCT04824248Recruiting
Weight Reduction in CLBP
The Added Value of a Behavioral Weight Reduction Program to Blended Rehabilitation in Patients With Chronic Low Back Pain: A Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 20 Aug 2026
Brief summary (registry, in English)
We will recruit overweight/ obese participants between the age of 18 and 65 with chronic nonspecific low back pain . The participants will be randomly assigned to one of two interventions (each lasting 10 weeks). All interventions will be delivered in a blended format and will be a combination of online education material and face-to-face sessions with a physical therapist. The first group (experimental intervention) will receive a behavioral weight reduction program combined with pain neuroscience education plus cognition-targeted exercise therapy. Participants in the second group (control intervention) will receive pain neuroscience education and cognition-targeted exercise therapy alone. Allocation to the groups will be at random. Participants and assessors will be blinded for group allocation. The primary outcomes is pain intensity. Secondary outcomes include other pain related outcomes, body composition, physical activity, sedentary behavior, dietary intake and function.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 84 (estimated)
- First submitted
- 24 Mar 2021
- Start date
- 1 May 2025
- Primary completion date
- 1 Dec 2027
- Lead sponsor
- Vrije Universiteit Brussel
- Diseases
- Obesity
- NCT number
- NCT04824248
What you commit to
- Study type: Interventional
- Planned participants: 84
- From 1 May 2025 to the primary completion date, 1 Dec 2027
- 2 sites in 2 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently receiving dietary or exercise interventions
Other illness
- Evidence of specific spinal pathology (e.g., hernia, spinal stenosis, spondylolisthesis, infection, spinal fracture or malignancy)
- Evidence of a severe underlying comorbidity (e.g. diabetes, cardiovascular problems, metabolic diseases)
Other
- Leg pain of 7 or higher (on a maximum of 10) on a numeric rating scale
- BMI ≥ 40 kg/m2
- Being pregnant or given birth in the preceding year
Who the study is looking for
- Overweight (BMI ≥ 25 kg/m2) or obese (BMI ≥ 30 kg/m2) with chronic low back pain
- Non-specific low back pain for at least 3 months' duration
- Currently seeking care for low back pain
- Native Dutch speaker
- Access to internet and computer/tablet/smartphone
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Vrije Universiteit Brussel Coordinator of this site? Confirm its status | Brussels | Belgium | Recruiting |
| Rotterdam University of Applied Sciences Coordinator of this site? Confirm its status | Rotterdam | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.