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NCT04826744Recruiting

Frequency of Palpebral Involvement in Adult With Atopic Dermatitis

Frequency of Palpebral Involvement in Adult Atopic Dermatitis, in a Cohort of Patients From Lille and Rouen (France) ; a Multicenter Prospective Study

Source: ClinicalTrials.gov · Last updated 23 Dec 2025

Brief summary (registry, in English)

Atopic dermatitis is a common inflammatory skin disease, resulting from genetical, immunological and environmental factors. Head and neck are among the most frequent involved areas, almost 50% in adult patients according to most publications. Palpebral involvement is also common and a source of major quality of life impairment for patients. However, the real frequency of this palpebral involvement is unknown, only estimated about 20% in few studies. The treatment of this location remains difficult, regarding to the thickness of palpebral skin and proximity of the eye. To our knowledge, no prospective studies about allergological skin tests (such as patch-tests) in atopic patients with palpebral involvement had been conducted. Finally, atopic dermatitis is frequently associated with ophthalmological diseases such as conjunctivitis, keratoconus or cataract, which belong to the minor criteria of Hanifin and Rakja classification. A better knowledge of the atopic dermatitis palpebral involvement and the associated factors seems to be needed to improve the treatment and the quality of life of patients

Status (registry)
Recruiting
Study type
Observational
Enrollment
550 (estimated)
First submitted
16 Mar 2021
Start date
1 Sept 2021
Primary completion date
30 Jun 2026
Lead sponsor
University Hospital, Lille
NCT number
NCT04826744

What you commit to

  • Study type: Observational
  • Planned participants: 550
  • From 1 Sept 2021 to the primary completion date, 30 Jun 2026
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Personal history of uncontrolled asthma

Age

  • Age under 18

Other

  • No social insurance
  • Protective measures
  • Pregnancy or breast-feeding

Who the study is looking for

  • Atopic Dermatitis according to the revised Hanifin and Rakja criteria (UK Working Party)
  • Oral consent
  • Valid social insurance

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Hop Claude Huriez Chu Lille
Coordinator of this site? Confirm its status
LilleFranceRecruiting
Hopital Charles Nicolle Chu Rouen
Coordinator of this site? Confirm its status
RouenFranceRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.