NCT04833348Active, not recruiting
Quantification of Motor Function in Infants With Spinal Muscular Atrophy Treated With Innovative Therapies
Quantification of Motor Function in Infants With Spinal Muscular Atrophy Treated With Innovative Therapies, IMUSMA Project
Source: ClinicalTrials.gov · Last updated 15 Sept 2025
Brief summary (registry, in English)
The aim of the study is to propose a method for quantifying motor function in infants with spinal muscular atrophy treated with innovative therapies using inertial sensors.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 35 (actual)
- First submitted
- 23 Mar 2021
- Start date
- 20 Mar 2021
- Primary completion date
- 17 Mar 2025
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Spinal muscular atrophy
- NCT number
- NCT04833348
What you commit to
- Study type: Interventional
- Participants enrolled: 35
- From 20 Mar 2021 to the primary completion date, 17 Mar 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to innovative therapy
Other illness
- History of another disease impacting motor skills (neonatal suffering, etc.)
Other
- Non-consent of one of the holders of parental authority
- Respiratory instability (dependence on ventilatory support for more than 16 hours per day) or hemodynamics
Who the study is looking for
- Infants of both sexes
- Suffering from spinal muscular atrophy (diagnosis by genetic study "homozygous deletion of SMN1")
- Followed up by the Necker Neuromuscular Reference Center (GNMH)
- Eligible for innovative therapy (gene therapy or pharmacogenetics)
- age of onset of the disease \<1 year
- no severe respiratory impairment (dependence on ventilatory support for more than 16 hours per day) or bulbar involvement
- decision of treatment by a Multidisciplinary Consultation Meeting national of experts
- Benefiting from social security scheme
- Informed consent signed by holders of parental authority and the investigator
Age in the registry: - to 2 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Necker Enfants Malades Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.