NCT04848545Active, not recruiting
Endocrine Disrupting Chemical Exposure and Testicular Cancer
Prenatal Exposure to Endocrine Disrupting Chemicals and Risk of Testicular Cancer in Offspring
Source: ClinicalTrials.gov · Last updated 21 Apr 2021
Brief summary (registry, in English)
DISRUPT is a Danish nested case-control study that is currently being conducted to explore the impact of prenatal exposure to endocrine disrupting chemicals on testicular cancer risk (including histological sub-groups) with emphasis on the analysis of exposure mixtures. Pregnant mothers provided serum and amniotic fluid at recruitment up to 50 years ago. By registry linkage within highly reliable national population and disease registries cancer cases and matched controls will be identified. Levels of EDCs including DDT, DDE and other organochlorine pesticides, PCBs, PBDEs, PFAS, phthalates and triclosan will be quantified in cases whose sons develop testicular cancer during 40 year follow up and compared to controls.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 700 (estimated)
- First submitted
- 8 Apr 2021
- Start date
- 1 Jun 2020
- Primary completion date
- 31 Dec 2028
- Lead sponsor
- Copenhagen University Hospital, Rigshospitalet
- Diseases
- Childhood cancers
- NCT number
- NCT04848545
What you commit to
- Study type: Observational
- Planned participants: 700
- From 1 Jun 2020 to the primary completion date, 31 Dec 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- other cancer
Who the study is looking for
- Male
- Available stored maternal serum and/or maternal amniotic fluid
Age in the registry: 15 years to 50 years · Sex: Male · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Growth and Reproduction, Rigshospitalet Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
| EDMaRC, Rigshospitalet secton 5064 Coordinator of this site? Confirm its status | Copenhagen | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.