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NCT04848545Active, not recruiting

Endocrine Disrupting Chemical Exposure and Testicular Cancer

Prenatal Exposure to Endocrine Disrupting Chemicals and Risk of Testicular Cancer in Offspring

Source: ClinicalTrials.gov · Last updated 21 Apr 2021

Brief summary (registry, in English)

DISRUPT is a Danish nested case-control study that is currently being conducted to explore the impact of prenatal exposure to endocrine disrupting chemicals on testicular cancer risk (including histological sub-groups) with emphasis on the analysis of exposure mixtures. Pregnant mothers provided serum and amniotic fluid at recruitment up to 50 years ago. By registry linkage within highly reliable national population and disease registries cancer cases and matched controls will be identified. Levels of EDCs including DDT, DDE and other organochlorine pesticides, PCBs, PBDEs, PFAS, phthalates and triclosan will be quantified in cases whose sons develop testicular cancer during 40 year follow up and compared to controls.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
700 (estimated)
First submitted
8 Apr 2021
Start date
1 Jun 2020
Primary completion date
31 Dec 2028
Lead sponsor
Copenhagen University Hospital, Rigshospitalet
NCT number
NCT04848545

What you commit to

  • Study type: Observational
  • Planned participants: 700
  • From 1 Jun 2020 to the primary completion date, 31 Dec 2028
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • other cancer

Who the study is looking for

  • Male
  • Available stored maternal serum and/or maternal amniotic fluid

Age in the registry: 15 years to 50 years · Sex: Male · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Department of Growth and Reproduction, Rigshospitalet
Coordinator of this site? Confirm its status
CopenhagenDenmarkUnknown status
EDMaRC, Rigshospitalet secton 5064
Coordinator of this site? Confirm its status
CopenhagenDenmarkUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.