NCT04856384Completed
Effect of Variance on Error Correction During Coupling
Understanding the Effect of Variances on Precision in Predictive Coding When Walking to Music and Metronomes in Persons With Multiple Sclerosis With Progressive Subtypes.
Source: ClinicalTrials.gov · Last updated 27 Feb 2025
Brief summary (registry, in English)
This study is a case-control study, involving persons with progressive multiple sclerosis and healthy controls. The study contains 1 descriptive and 3 experimental sessions. In the descriptive session, participant's clinical motor and cognitive functions are collected. In the first experimental session, participant's beat perception and synchronisation abilities is examined within a finger tapping paradigm. In the following experimental sessions participants synchronsiation abilities is examined during walking paradigms, to music and metronomes, with period and phase auditory manipulations. In the latter twp sessions, apart from outcome measures of synchronization the following will be collected as well: brain activity using EEG recordings, spatio-temporal gait parameters, perceived fatigue, perceived motivation and perceived speed of walking.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 13 (actual)
- First submitted
- 29 Jan 2021
- Start date
- 1 Feb 2021
- Primary completion date
- 22 Oct 2024
- Lead sponsor
- Hasselt University
- Diseases
- Multiple sclerosis
- NCT number
- NCT04856384
What you commit to
- Study type: Interventional
- Participants enrolled: 13
- From 1 Feb 2021 to the primary completion date, 22 Oct 2024
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- relapse 3 months prior to enrollment,
Other illness
- cognitive impairment impeding understanding of instructions,
Other
- beat amusia,
- deafness,
- pregnancy
Who the study is looking for
- diagnosis of Multiple sclerosis \>1 year, diagnosis of progressive MS,
- walking speed 0.8-1.2m/s, ability to walk for 6 minutes continuously (canes and rollators are permitted)
Age in the registry: 18 years to 70 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National MS Center Melsbroek Coordinator of this site? Confirm its status | Melsbroek | Belgium | Unknown status |
| Noorderhart Revalidatie & MS centrum Coordinator of this site? Confirm its status | Overpelt | Belgium | Unknown status |
Related publications
- Technology-Assisted Solutions to Enhance Auditory-Motor Synchronization During Walking in Progressive Multiple Sclerosis.Neurorehabil Neural Repair · 2026 · PMID 41645795
This page is information, not medical advice. Discuss any trial with your doctor.