NCT04863677Completed
The Effect of HIIT, MICT in Patients With Myocardial Infarction
Effect of High-Intensity Interval Training, Moderate Continuous Training, or Guideline-Based Physical Activity on Peak Oxygen Uptake and Myocardial Fibrosis in Patients With Myocardial Infarction: Protocol for a Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 3 Feb 2026
Brief summary (registry, in English)
This study will investigate the effect of a 12-weeks cardiac rehabilitation training (HIIT, MICT) program on VO2peak and cardiac fibrosis in patients, and evaluate the effects of HIIT on endothelial function, microvascular obstruction, body fat, inflammation, arrhythmia and psychology .
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 188 (actual)
- First submitted
- 22 Apr 2021
- Start date
- 1 May 2021
- Primary completion date
- 30 Sept 2025
- Lead sponsor
- Guangdong Provincial People's Hospital
- Diseases
- Coronary artery disease
- NCT number
- NCT04863677
What you commit to
- Study type: Interventional
- Participants enrolled: 188
- From 1 May 2021 to the primary completion date, 30 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Have any other diseases which limit their life to less than a year (e.g. severe valvular disease, recurrent ventricular arrhythmias, NYHA Class IV heart failure, severe aortic incompetence, severe atrial fibrillation, cancers, and end-stage renal or liver disease)
- Dementia ; disability or sports contraindication
- Severe acute liver failure
- Severe acute renal failure
Other
- High-intensity exercise frequently
- Currently participating in any other clinical trials
- Unstable vital signs
- Site investigators consider that the patient will be unable to complete the study and/or attend for follow-up.
Who the study is looking for
- Aged 18 -75 years
- Acute myocardial infarction (AMI) patients between 6 weeks and 3 months and had been underwent revascularization, and New York Heart Association functional classification (NYHA) Class I-III; (AMI confirmed by the World Health Organization definition (presence of symptoms of ischemia and changes in electrocardiogram) or the Third Universal Definition of Myocardial Infarction (elevation of a cardiac biomarker along with presence of either symptoms of myocardial infarction or changes in electrocardiogram))
- Willing and able to attend the complete cardiac rehabilitation(CR)program on their own，assigned the Informed consent form.
- Complete the cardiopulmonary exercise testing (CPET) at enrollment or has the CPET report within 1 month.
Age in the registry: 18 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital Coordinator of this site? Confirm its status | Guangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.