NCT04869631Active, not recruiting
Screening for Amyloidosis Before Aortic Valve Elective Replacement
Screening for Amyloidosis Before Aortic Valve Elective Replacement (SAVER)
Source: ClinicalTrials.gov · Last updated 12 Feb 2025
Brief summary (registry, in English)
Previous studies detected that up to 15% of patients undergoing aortic valve replacement (AVR) for degenerative aortic stenosis have concomitant transthyretin amyloidosis (ATTR) cardiomyopathy (Castano, 2017). The aim of this study is to investigate the effectivity and practicability of a systematic ATTR-Screening in patients undergoing planned AVR. Moreover, we plan to develop a screening algorithm to detect ATTR in aortic stenosis (AS).
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 1000 (actual)
- First submitted
- 28 Apr 2021
- Start date
- 1 Feb 2021
- Primary completion date
- 31 Mar 2023
- Lead sponsor
- Charite University, Berlin, Germany
- Diseases
- Amyloidosis
- NCT number
- NCT04869631
What you commit to
- Study type: Observational
- Participants enrolled: 1000
- From 1 Feb 2021 to the primary completion date, 31 Mar 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- hemodynamically unstable patient
- severe co-morbidities with an estimated life expectancy of \<1 year
Who the study is looking for
- age ≥40 years
- written informed consent from the patient or of his/her legal guardian
- hospitalization for AVR due to degenerative aortic valve stenosis
Age in the registry: 40 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Charité Universitätsmedizin Berlin Coordinator of this site? Confirm its status | Berlin | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.