NCT04874012RecruitingPhase 2
Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes
Effect of Taurine on Glycemic, Lipid and Inflammatory Profile in Individuals With Type 2 Diabetes: a Randomized Clinical Trial
Source: ClinicalTrials.gov · Last updated 24 Sept 2026
Brief summary (registry, in English)
Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do not reach the glycemic targets, requiring adjuvant therapies. Taurine is a semi-essential amino acid with antioxidant and osmoregulatory properties, commonly used as a nutritional supplement. Pre-clinical studies show its effectiveness in reducing blood glucose and cholesterol, but there are no well-conducted clinical studies evaluating the effect of taurine on glycated hemoglobin. Additionally, animal models showed that taurine had a protective effect from diabetic nephropathy. The hypothesize of this study is that taurine administration improves the glycemic, lipid, inflammatory, and anthropometric parameters in DM2 individuals.
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 94 (estimated)
- First submitted
- 30 Apr 2021
- Start date
- 12 Jun 2021
- Primary completion date
- 20 Dec 2025
- Lead sponsor
- Hospital de Clinicas de Porto Alegre
- Diseases
- Type 2 diabetes
- NCT number
- NCT04874012
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 94
- From 12 Jun 2021 to the primary completion date, 20 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Bariatric surgery.
Other illness
- Chronic renal failure with glomerular filtration rate calculated by MDRD \< 30 mL/h;
- Myocardial infarction in the last than 6 months
Other
- Use of herbal supplements, antioxidants, and multivitamins in the last 3 months;
- Pregnancy or lactation;
- Current neoplasia;
- Chronic use of glucocorticoids;
Who the study is looking for
- Female and male individuals, with clinical diagnosis of DM2 for at least 6 months;
- Age over 30 years;
- BMC equal to or above 18.5 kg/m2, without weight change in the last 3 months;
- HbA1c between 7.5% and 10.5%.
Age in the registry: 30 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital de Clínicas Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.