NCT04874909Completed
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)
Classification and Functional Stratification of the Patients With Ciliopathy and Identification of Biomarkers to Improve Their Prognosis
Source: ClinicalTrials.gov · Last updated 6 May 2026
Brief summary (registry, in English)
The purpose of the C'IL-LICO RICM study is to develop innovative and transformative diagnostic and prognostic for patients suffering from ciliopathies leading to renal failure. The objectives is to decipher disease mechanisms and highlight signaling pathways altered in at-risk to develop renal failure patient groups and to produce a prognostic biomarker-based kit to predict the evolution of ciliopathy patients towards renal impairment.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 240 (actual)
- First submitted
- 31 Mar 2021
- Start date
- Nov 2021
- Primary completion date
- Oct 2024
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Chronic kidney disease
- NCT number
- NCT04874909
What you commit to
- Study type: Interventional
- Participants enrolled: 240
- From Nov 2021 to the primary completion date, Oct 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- use an experimental treatment during 30 days before inclusion date
- Healthy related individual :
- \- pregnant, parturious and nursing mothers.
- "Negative Control" patient :
- \- pregnant, parturious and nursing mothers.
- "Positive Control" patient :
- use an experimental treatment during 30 days before inclusion date
Other
- pregnant, parturious and nursing mothers.
- with functional renal graft
- pregnant, parturious and nursing mothers.
- with functional renal graft
Who the study is looking for
- "Case" Patient :
- with nephronophthisis or ciliopathy with known genetic diagnosis or not
- signed the Informed consent form (patient or legal guardians if minor/incapable major)
- no limit of age, this patients could be recruited from the birth
- social insurance affiliation
- Healthy related individual :
- related with a included patient (father, mother, brother, sister)
- signed the Informed consent form (major or legal guardians if minor/incapable major)
- no limit of age, this patients could be recruited from the birth
- social insurance affiliation
- "Negative Control" patient :
- without chronic renal failure
- signed the Informed consent form (major or legal guardians if minor/incapable major)
- no limit of age, this patients could be recruited from the birth
- social insurance affiliation
- "Positive Control" patient :
- with chronic renal failure not related with a ciliary dysfunction
- signed the Informed consent form (major or legal guardians if minor/incapable major)
- no limit of age, this patients could be recruited from the birth
- social insurance affiliation
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hopital Necker Enfants Malades Coordinator of this site? Confirm its status | Paris | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.