NCT04890054Completed
Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC
Screening More Patients for CRC Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings (SMARTER CRC)
Source: ClinicalTrials.gov · Last updated 19 Aug 2025
Brief summary (registry, in English)
This study collects information to provide a model for how to rapidly adapt and scale-up multilevel interventions through clinic-health plan partnerships to reduce the burden of colorectal cancer (CRC) on the United states population. This study may improve colorectal cancer screening rates, follow-up colonoscopy, and referral to care in rural Medicaid patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 5696 (actual)
- First submitted
- 12 May 2021
- Start date
- 14 May 2021
- Primary completion date
- 1 Jul 2024
- Lead sponsor
- OHSU Knight Cancer Institute
- Diseases
- Colorectal cancer
- NCT number
- NCT04890054
What you commit to
- Study type: Interventional
- Participants enrolled: 5696
- From 14 May 2021 to the primary completion date, 1 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- PATIENTS: Comorbid conditions that make patients poor candidates for screening based on clinical judgment (e.g., end-stage renal disease, enrollment in hospice)
Age
- All patients that we recruit will be at least 45 years of age or older
Other
- CLINICS: Clinics are excluded if they have current or ongoing participating in other mailed fecal testing research projects in the Medicaid population
- PATIENTS: Are current for screening
- PATIENTS: Are not an established patient or for other reasons documented by the clinics
Who the study is looking for
- CCOs/CCO STAFF: Serving a majority of counties that are predominantly rural based on 2010 Rural-Urban Commuting Area (RUCA) codes (codes 4-10)
- CCOs/CCO STAFF: Willing to participate in data collection activities (e.g., producing claims data, interviews)
- CLINICS: Clinics will be eligible for the cluster randomization if there are 30 or more patients eligible for screening
- CLINICS: Are classified as rural according to RUCA (Codes 4-10) or Oregon Office of Rural Health designations
- CLINICS: Are served by CCOs agreeing to participate in the project
- CLINICS: Willing to implement the intervention into their clinic for the study
- CLINIC STAFF/PROVIDERS: Employed as a clinician or ancillary staff member in a participating clinic
- CLINIC STAFF/PROVIDERS: Willing to participate in data collection activities (e.g., interviews, observation, surveys)
- PATIENTS: Attributed to participating clinic
- PATIENTS: Are enrolled in Medicaid or dual eligible
- PATIENTS: Eligible for colorectal cancer (CRC) screening
- PATIENTS: For the subset of patients that will be invited to participate in key informant interviews, a 5th eligibility criteria is consented to participate
- COMMUNITY OR REGIONAL/ORGANIZATIONAL PARTNERS: (Includes endoscopy providers, community-based outreach workers, or leaders from regional or national organizations who participate in the pilot, pragmatic trial, or scale-up study)
- COMMUNITY OR REGIONAL/ORGANIZATIONAL PARTNERS: Involved in study activities (training, care delivery)
- COMMUNITY OR REGIONAL/ORGANIZATIONAL PARTNERS: Willing to participate in data collection activities (e.g., trainings, interviews, surveys)
- Elderly - Yes - we anticipate that a limited number of clinic and CCO staff, or community organization representatives may be elderly; we limit our patient recruitment to those aged 45-75
- Rural - Yes
- Inner city - No
- Low income - Yes
- Disabled - Yes
- Chronic care - Yes
- End of life - Yes - This is possible, but we predict limited numbers because of the types of individuals we are recruiting: clinic and CCO staff, and patients who are not currently in hospice care
- Minorities - Yes
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| OHSU Knight Cancer Institute Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
Related publications
- Scale-up evaluation results of a multi-level approach using mailed immunochemical test (FIT) and patient navigation to increase colorectal cancer screening rates in rural clinic settings.BMC Prim Care · 2026 · PMID 42449237
- Facilitation of Health Plan-Clinic Partnerships to Improve Colorectal Cancer Screening for Rural Medicaid Enrollees: A Qualitative Study.J Rural Health · 2026 · PMID 42572815
This page is information, not medical advice. Discuss any trial with your doctor.