NCT04897334Recruiting
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke
Transcranial Direct Current Stimulation and Rehabilitation to Ameliorate Impairments in Neurocognition After Stroke (TRAINS): Neuromodulatory Intervention to Ameliorate Cognition After Stroke for Individuals At Risk for VCID.
Source: ClinicalTrials.gov · Last updated 9 Jan 2026
Brief summary (registry, in English)
The purpose of this study is to determine whether a non-invasive brain stimulation technique, transcranial direct current stimulation (tDCS), combined with traditional cognitive therapy will improve cognitive function in patients with subacute stroke.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 17 May 2021
- Start date
- 21 Sept 2021
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- University of Pennsylvania
- Diseases
- Stroke
- NCT number
- NCT04897334
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 21 Sept 2021 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current abuse of alcohol or drugs (prescription or otherwise)
- Metallic objects in the face or head other than dental apparatus such as braces, fillings, and implants.
Other illness
- History of chronic, serious, or unstable neurologic illness other than stroke
- Current unstable medical illness(es)
- History of reoccurring seizures or epilepsy
- Active and severe psychiatric disorder
Other
- Pregnancy
Who the study is looking for
- Stroke that occurred within 4 weeks of the study
- Presence of cognitive impairment attributable to stroke
- Between the ages of 18 and 90
- Able to understand the nature of the study and give informed consent
- Able to follow simple commands as evidenced by NIHSS subtest 1C =0
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Penn Medicine Rehabilitation Coordinator of this site? Confirm its status | Philadelphia | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.