NCT04899063Completed
Excimer Laser Trabeculostomy Glaucoma Treatment Study
A Prospective, Multicenter Clinical Trial Designed to Evaluate the Safety and Effectiveness of the ELIOS System to Reduce Intraocular Pressure in Patients With Primary Open-Angle Glaucoma Undergoing Cataract Surgery
Source: ClinicalTrials.gov · Last updated 16 Jun 2026
Brief summary (registry, in English)
Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG) undergoing cataract surgery
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 318 (actual)
- First submitted
- 19 May 2021
- Start date
- 10 May 2021
- Primary completion date
- 29 Jul 2025
- Lead sponsor
- Elios Vision, Inc.
- Diseases
- Glaucoma
- NCT number
- NCT04899063
What you commit to
- Study type: Interventional
- Participants enrolled: 318
- From 10 May 2021 to the primary completion date, 29 Jul 2025
- 20 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior incisional glaucoma surgery, intraocular surgery, or corneal surgery
- Cannot undergo medication washout in the study eye
- Known corticosteroid responder
Other illness
- Diagnosis of degenerative visual disorders
Other
- Closed-angle and secondary glaucomas
- Non-study eye with BCVA worse than 20/80
- Pregnant or nursing women; or women of childbearing potential not using medically acceptable birth control
Who the study is looking for
- Diagnosis of mild to moderate POAG
- Operable cataract, eligible for phacoemulsification with a BCVA of 20/40 or worse
- Medicated IOP of \<=24 mmHg
- Unmedicated diurnal IOP of \>=22 mmHg and \<=34 mmHg
- Shaffer angle grade of III or IV
- CD ratio \<=0.8
- At least 45 years old
Age in the registry: 45 years to - · Sex: All · Does not accept healthy volunteers
Sites (20)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Chaska | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | DeLand | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Duncanville | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | El Paso | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Fort Collins | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | Glendale | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Grand Junction | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | Kenosha | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Largo | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Las Vegas | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Melbourne | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | Oklahoma City | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Overland Park | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Petaluma | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | Rock Island | United States | Unknown status |
| Elios Vision Clinical Site 2 Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | San Antonio | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | South Orange | United States | Unknown status |
| Elios Vision Clinical Site Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
| ELIOS Vision Clinical Site Coordinator of this site? Confirm its status | Vero Beach | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.