NCT04903717Completed
Pragmatic Trial Of Alerts for Use of Mineralocorticoid Receptor Antagonists
Pragmatic Trial Of Messaging to Providers About Treatment With Mineralocorticoid Receptor Antagonists
Source: ClinicalTrials.gov · Last updated 23 Aug 2024
Brief summary (registry, in English)
The primary objective of this study is to determine if a best practice alert (BPA) system that prompts providers to consider the addition of a mineralocorticoid receptor antagonist (MRA) in eligible patients with heart failure with reduced ejection fraction (HFrEF) will result in increased prescription of this guideline-recommended therapy. The system will also inform providers about FDA-approved potassium binders for the treatment of hyperkalemia if elevated potassium is a barrier for MRA use and will provide educational information on the evidence for MRA therapy in these patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 1210 (actual)
- First submitted
- 21 May 2021
- Start date
- 3 Nov 2021
- Primary completion date
- 6 Aug 2023
- Lead sponsor
- Yale University
- Diseases
- Heart failure
- NCT number
- NCT04903717
What you commit to
- Study type: Interventional
- Participants enrolled: 1210
- From 3 Nov 2021 to the primary completion date, 6 Aug 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Absolute contraindication to MRAs
Who the study is looking for
- Adults equal to or greater than 18 years of age
- Outpatients of providers randomized into the study within Internal Medicine and Cardiology outpatient clinics
- Diagnosis of heart failure with reduced ejection fraction (LVEF less than or equal to 40% on the most recent TTE)
- Registration in the Yale Heart Failure Registry (NCT04237701)
- Not currently prescribed an MRA
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cardiology/Internal Medicine Outpatient Clinics of Yale New Health System Coordinator of this site? Confirm its status | New Haven | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.