NCT04905238Completed
Obstructive Sleep Apnea and Biomarkers of Alzheimer's Disease
Pathophysiology Consequences of Obstructive Sleep Apnea in Biomarkers of Alzheimer's Disease. A Clinical Trial
Source: ClinicalTrials.gov · Last updated 5 Nov 2026
Brief summary (registry, in English)
Clinical trial on the effect of continuous positive pressure (CPAP). Objectives: 1) To compare biomarkers of Alzheimer's disease in plasma samples from patients with Obstructive sleep apnea (OSA) and without OSA. 2) To determine if CPAP reduces biomarkers of Alzheimer's disease in plasma samples.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 136 (actual)
- First submitted
- 24 May 2021
- Start date
- 31 Jul 2020
- Primary completion date
- 6 Jul 2026
- Lead sponsor
- Alberto Alonso Fernandez
- Diseases
- Alzheimer disease
- NCT number
- NCT04905238
What you commit to
- Study type: Interventional
- Participants enrolled: 136
- From 31 Jul 2020 to the primary completion date, 6 Jul 2026
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concomitant treatment with antihypertensives, statins, antidiabetics, beta- blockers or systemic corticosteroids.
- Participation in another clinical trial thirty days prior to randomization
Other illness
- Arterial Hypertension
- Diabetes Mellitus
- Cerebrovascular disease
- Ischemic heart disease
- Cardiac arrhythmia
- Chronic cardiovascular diseases
Other
- Epworth\>18
- BMI\<40Kg/M2
- Daytime Oxygen saturation\>95%
- Risk professions (professional drivers)
- Pretreatment with CPAP.
- Abnormal values of a cognitive test.
Who the study is looking for
- Cases: patients with AHI \> 30/h
- Controls: subjects with AHI \< 5/h and Epworth \<10
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Son Llatzer Coordinator of this site? Confirm its status | Palma | Spain | Unknown status |
| Hospital Son Espases Coordinator of this site? Confirm its status | Palma | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.