NCT04908423RecruitingPhase 4
Xeomin® and Gait Related Mobility After Stroke
Upper Extremity Injection of Xeomin® and Changes in Gait Related Mobility in Adults After Stroke
Source: ClinicalTrials.gov · Last updated 26 Oct 2026
Brief summary (registry, in English)
The aim of the present pilot study is to evaluate the association between change in gait related mobility in ambulatory male and female adult hemiparetic patients before and 4-6-weeks after Xeomin® injection into the upper limb, using two standardized tests of physical function in outpatient rehabilitation that are widely used; the 10-meter walk test and the timed 'up and go' test (TUG).
- Status (registry)
- Recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- First submitted
- 25 May 2021
- Start date
- 19 Oct 2021
- Primary completion date
- Apr 2028
- Lead sponsor
- Wake Forest University Health Sciences
- Diseases
- Stroke
- NCT number
- NCT04908423
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 20
- From 19 Oct 2021 to the primary completion date, Apr 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Weight bearing restrictions due to concurrent orthopedic injuries that would make ambulating with or without an assistive device unsafe
Other illness
- Participants with uncorrected hearing impairment
- Other confounding neurological diagnoses or active acute illness (cancer, Parkinson's disease, multiple sclerosis)
Other
- Passive range of motion at either the ankle, knee, or elbow joint less than 30 degrees
- Speech language expression deficit (e.g., aphasia)
- Absence of proprioception upon neurologic examination
- Presence of fixed contractures in the upper or lower extremities not correctable to neutral
Who the study is looking for
- Diagnosis of hemiparesis and spasticity secondary to stroke with upper and lower limb spasticity and unilateral motor and/or sensory deficit
- No prior surgery to the lower limb
- Able to walk at least 10 meters without physical assistance from another person and without an assistive device
- Toe- ground clearance during swing phase without assistive device or orthoses
- No treatment with botulinum toxin within the past 4 months
Age in the registry: 18 years to 79 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Carolinas Rehabilitation Coordinator of this site? Confirm its status | Charlotte | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.