NCT04912687Completed
Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced NSCLC Patients
Implementing Circulating Tumor DNA Analysis at Initial Diagnosis to Improve Management of Advanced Non-small Cell Lung Cancer Patients (NSCLC)
Source: ClinicalTrials.gov · Last updated 6 Mar 2026
Brief summary (registry, in English)
Multicenter prospective cohort study aiming to evaluate the detection rate of EGFR gene mutation in patients with advanced NSCLC in a real-word clinical setting, based on liquid biopsy and tissue analyses.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 581 (actual)
- First submitted
- 28 May 2021
- Start date
- 1 Jan 2022
- Primary completion date
- 17 Jan 2026
- Lead sponsor
- Institut Bergonié
- Diseases
- Lung cancer
- NCT number
- NCT04912687
What you commit to
- Study type: Interventional
- Participants enrolled: 581
- From 1 Jan 2022 to the primary completion date, 17 Jan 2026
- 9 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Treatment for advanced NSCLC started before liquid biopsy sampling.
- Involvement in the planning and/or conduct of the study (applies to both Investigator staff and/or staff at the study site).
Who the study is looking for
- Male or female patients aged ≥ 18 years at time of proposal study,
- Histologically confirmed non-small cell lung carcinoma,
- No previous treatment for NSCLC,
- Indication to EGFR status determination following HAS recommendation,
- Voluntary signed and dated written informed consent prior to any study specific procedure
- Patients with a social security in compliance with the French Law.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (9)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut de Cancérologie de l'Ouest - Site Paul Papin Coordinator of this site? Confirm its status | Angers | France | Unknown status |
| Institut Bergonie Coordinator of this site? Confirm its status | Bordeaux | France | Unknown status |
| CHRU Lille Coordinator of this site? Confirm its status | Lille | France | Unknown status |
| Hospices Civils de Lyon Coordinator of this site? Confirm its status | Lyon | France | Unknown status |
| CHU Nice-Hopital de Cimiel Coordinator of this site? Confirm its status | Nice | France | Unknown status |
| Institut Curie Coordinator of this site? Confirm its status | Paris | France | Unknown status |
| CHU Poitiers Coordinator of this site? Confirm its status | Poitiers | France | Unknown status |
| CHU de Rennes - Hôpital Pontchaillou Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| CHU Strasbourg Coordinator of this site? Confirm its status | Strasbourg | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.