NCT04930159Active, not recruiting
Social Interventions for Support During Treatment for Endometrial Cancer and Recurrence
Source: ClinicalTrials.gov · Last updated 28 Apr 2026
Brief summary (registry, in English)
The SISTER study is a randomized trial, looking at various modalities of social support for Black patients undergoing treatment for endometrial cancer. There are three study arms: group support, 1:1 peer support, and enhanced usual care. The primary outcome is treatment completion, and the secondary outcome is social isolation.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 252 (actual)
- First submitted
- 11 Jun 2021
- Start date
- 1 Sept 2021
- Primary completion date
- 7 Apr 2026
- Lead sponsor
- University of Washington
- Diseases
- Endometrial cancer
- NCT number
- NCT04930159
What you commit to
- Study type: Interventional
- Participants enrolled: 252
- From 1 Sept 2021 to the primary completion date, 7 Apr 2026
- 11 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Enrollment into hospice prior to randomization
Other illness
- Previous history of other cancer diagnosis requiring chemotherapy, radiation therapy, or immunotherapy within the past 12 months;
- Contraindication to all non-surgical therapy available for endometrial cancer (i.e., chemotherapy, radiation, and immunotherapy contraindicated);
- Recent hospitalization for psychiatric illness in the past 6 months
Other
- Participants must not have any of the following exclusion criteria:
- Newly diagnosis of FIGO Stage IA Grade 1 endometrioid adenocarcinoma
- Incarcerated in a detention facility or in police custody (patients wearing a monitoring device can be enrolled) at baseline/screening;
- Unable to provide written informed consent in English;
- Unable to be contacted for research surveys;
Who the study is looking for
- Adult 18 years of age or older; and
- Self-identify as Black/African American
- Presenting with high-risk EC established by anatomic pathology as tumor stage and grade classification by the following:
- Pathology documentation from any hospital/clinic/medical center, and
- FIGO Stage 1A with Grade 2, Grade 3, or Grade 4 of any histology type or
- FIGO Stage 1A with non-endometrioid (carcinosarcoma, serous, clear cell, undifferentiated or mixed) histology
- FIGO Stage 1B, 2, 3, or 4 of any grade or histology
- Recurrent endometrial cancer of any stage or grade
- Documented provider recommendation and patient plan to initiate adjuvant therapy with chemotherapy, radiation, and/or immunotherapy.
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Johns Hopkins University Coordinator of this site? Confirm its status | Baltimore | United States | Unknown status |
| University of Alabama Coordinator of this site? Confirm its status | Birmingham | United States | Unknown status |
| University of North Carolina Coordinator of this site? Confirm its status | Chapel Hill | United States | Unknown status |
| The University Of Chicago Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
| University Hospitals Cleveland Medical Center* Coordinator of this site? Confirm its status | Cleveland | United States | Unknown status |
| MedStar Health Research Institute Coordinator of this site? Confirm its status | Columbia | United States | Unknown status |
| University of Arkansas for Medical Sciences Coordinator of this site? Confirm its status | Little Rock | United States | Unknown status |
| University of Miami Coordinator of this site? Confirm its status | Miami | United States | Unknown status |
| Louisiana State University - New Orleans Coordinator of this site? Confirm its status | New Orleans | United States | Unknown status |
| Weill Cornell Medicine Coordinator of this site? Confirm its status | New York | United States | Unknown status |
| Fred Hutch/University of Washington Cancer Consortium Coordinator of this site? Confirm its status | Seattle | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.