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NCT04930159Active, not recruiting

Social Interventions for Support During Treatment for Endometrial Cancer and Recurrence

Source: ClinicalTrials.gov · Last updated 28 Apr 2026

Brief summary (registry, in English)

The SISTER study is a randomized trial, looking at various modalities of social support for Black patients undergoing treatment for endometrial cancer. There are three study arms: group support, 1:1 peer support, and enhanced usual care. The primary outcome is treatment completion, and the secondary outcome is social isolation.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
252 (actual)
First submitted
11 Jun 2021
Start date
1 Sept 2021
Primary completion date
7 Apr 2026
Lead sponsor
University of Washington
NCT number
NCT04930159

What you commit to

  • Study type: Interventional
  • Participants enrolled: 252
  • From 1 Sept 2021 to the primary completion date, 7 Apr 2026
  • 11 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Enrollment into hospice prior to randomization

Other illness

  • Previous history of other cancer diagnosis requiring chemotherapy, radiation therapy, or immunotherapy within the past 12 months;
  • Contraindication to all non-surgical therapy available for endometrial cancer (i.e., chemotherapy, radiation, and immunotherapy contraindicated);
  • Recent hospitalization for psychiatric illness in the past 6 months

Other

  • Participants must not have any of the following exclusion criteria:
  • Newly diagnosis of FIGO Stage IA Grade 1 endometrioid adenocarcinoma
  • Incarcerated in a detention facility or in police custody (patients wearing a monitoring device can be enrolled) at baseline/screening;
  • Unable to provide written informed consent in English;
  • Unable to be contacted for research surveys;

Who the study is looking for

  • Adult 18 years of age or older; and
  • Self-identify as Black/African American
  • Presenting with high-risk EC established by anatomic pathology as tumor stage and grade classification by the following:
    • Pathology documentation from any hospital/clinic/medical center, and
    • FIGO Stage 1A with Grade 2, Grade 3, or Grade 4 of any histology type or
    • FIGO Stage 1A with non-endometrioid (carcinosarcoma, serous, clear cell, undifferentiated or mixed) histology
    • FIGO Stage 1B, 2, 3, or 4 of any grade or histology
    • Recurrent endometrial cancer of any stage or grade
  • Documented provider recommendation and patient plan to initiate adjuvant therapy with chemotherapy, radiation, and/or immunotherapy.

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Johns Hopkins University
Coordinator of this site? Confirm its status
BaltimoreUnited StatesUnknown status
University of Alabama
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BirminghamUnited StatesUnknown status
University of North Carolina
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Chapel HillUnited StatesUnknown status
The University Of Chicago
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ChicagoUnited StatesUnknown status
University Hospitals Cleveland Medical Center*
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ClevelandUnited StatesUnknown status
MedStar Health Research Institute
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ColumbiaUnited StatesUnknown status
University of Arkansas for Medical Sciences
Coordinator of this site? Confirm its status
Little RockUnited StatesUnknown status
University of Miami
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MiamiUnited StatesUnknown status
Louisiana State University - New Orleans
Coordinator of this site? Confirm its status
New OrleansUnited StatesUnknown status
Weill Cornell Medicine
Coordinator of this site? Confirm its status
New YorkUnited StatesUnknown status
Fred Hutch/University of Washington Cancer Consortium
Coordinator of this site? Confirm its status
SeattleUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.